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Myasthenic Syndromes in Hypothyroidism: Electrophysiological Study of Neuromuscular Transmission and Muscle Contraction in Two Patients
Journal article   Peer reviewed

Myasthenic Syndromes in Hypothyroidism: Electrophysiological Study of Neuromuscular Transmission and Muscle Contraction in Two Patients

Masaharu Takamori, Ludwig Gutmann, Thomas W Crosby and James D Martin
Archives of neurology (Chicago), Vol.26(4), pp.326-335
04/01/1972
DOI: 10.1001/archneur.1972.00490100056005
PMID: 4335614

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Abstract

Two hypothyroid patients, one with autoimmune thyroiditis and pernicious anemia and the other with idiopathic primary myxedema, were studied electrophysiologically. The former showed findings of the Eaton-Lambert myasthenic syndrome, and the latter showed findings of the desensitization block of neuromuscular transmission or the conduction block at the fine terminal filaments of the motor axon. The muscle contraction study revealed the posttetanic muscle contracture without electrical discharges in the former, and the posttetanic twitch depression and the decreased tetanic force in the latter.

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