Journal article
Myoinositol uptake by four cultured mammalian cell lines
Archives of biochemistry and biophysics, Vol.246(2), pp.801-807
1986
DOI: 10.1016/0003-9861(86)90336-X
PMID: 3458428
Abstract
The uptake of myo-[2-
3H]inositol by mouse neuroblastoma, human Y79 retinoblastoma, human HL60, and bovine pulmonary artery endothelial cells occurs by a saturable, Na
+-dependent and partially energy-dependent mechanism. Inositol uptake by all four cell lines occurred by both a high- and low-affinity system. The kinetic parameters for the high-affinity uptake systems were similar for all four cell lines. These data suggest that all four of these diverse cell lines have similar inositol transport systems and probably rely on extracellular inositol for anabolic processes.
Details
- Title: Subtitle
- Myoinositol uptake by four cultured mammalian cell lines
- Creators
- Mark A Yorek - Veterans Administration Medical Center, Iowa City, Iowa 52240, USAJoyce A Dunlap - Veterans Administration Medical Center, Iowa City, Iowa 52240, USABarry H Ginsberg - Veterans Administration Medical Center, Iowa City, Iowa 52240, USA
- Resource Type
- Journal article
- Publication Details
- Archives of biochemistry and biophysics, Vol.246(2), pp.801-807
- Publisher
- Elsevier Inc
- DOI
- 10.1016/0003-9861(86)90336-X
- PMID
- 3458428
- ISSN
- 0003-9861
- eISSN
- 1096-0384
- Language
- English
- Date published
- 1986
- Academic Unit
- Fraternal Order of Eagles Diabetes Research Center; Endocrinology and Metabolism; Internal Medicine
- Record Identifier
- 9984094751602771
Metrics
11 Record Views