N-butyl cyanoacrylate embolization using a detachable tip microcatheter: initial experience

Srinivasan Paramasivam; David Altschul; Santiago Ortega-Gutiarrez; Johanna Fifi; Alejandro Berenstein

doi:10.1136/neurintsurg-2014-011165

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N-butyl cyanoacrylate embolization using a detachable tip microcatheter: initial experience

Journal article

Peer reviewed

N-butyl cyanoacrylate embolization using a detachable tip microcatheter: initial experience

Srinivasan Paramasivam, David Altschul, Santiago Ortega-Gutiarrez, Johanna Fifi and Alejandro Berenstein

Journal of neurointerventional surgery, Vol.7(6), pp.458-461

06/2015

DOI: 10.1136/neurintsurg-2014-011165

PMID: 24714611

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Abstract

Endovascular embolization of intracranial vascular malformations with N-butyl cyanoacrylate (nBCA) using a detachable tip microcatheter allows prolonged injection and decreases the risk of catheter retention. Between March and December 2013, the Apollo 1.5 cm detachable tip microcatheter was used in five patients after being approved by both the Food and Drug Administration and the institutional review board as a compassionate use device. Nine pedicles were embolized and the follow-up ranged from 1 to 3 months. Five of the nine catheter tips detached. The length of reflux was not directly associated with the detachment of the distal tip. There were no cases of premature microcatheter detachment during navigation, manipulation with multiple microguidewire reintroduction and guidance. There was no leak of embolic agent at the detachment zone. Follow-up showed the detached tip to be stable without migration. A detachable tip microcatheter offers an advance in the safety and effectiveness of nBCA embolization. Catheter retrieval becomes more controlled and less traumatic. Our initial experience is encouraging, and more experience is needed to categorically ascertain its safety and efficacy.

Embolization, Therapeutic - instrumentation

Follow-Up Studies

Humans

Child, Preschool

Infant

Treatment Outcome

Young Adult

Vascular Access Devices - standards

Embolization, Therapeutic - standards

Adult

Intracranial Arteriovenous Malformations - therapy

Embolization, Therapeutic - methods

Enbucrilate - administration & dosage

Details

Title: Subtitle: N-butyl cyanoacrylate embolization using a detachable tip microcatheter: initial experience
Creators: Srinivasan Paramasivam - Hyman Newman Institute for Neurology and Neurosurgery, Centre for Endovascular Surgery, Roosevelt Hospital, Mount Sinai Health Stystem, New York, New York, USA
David Altschul - Hyman Newman Institute for Neurology and Neurosurgery, Centre for Endovascular Surgery, Roosevelt Hospital, Mount Sinai Health Stystem, New York, New York, USA
Santiago Ortega-Gutiarrez - Hyman Newman Institute for Neurology and Neurosurgery, Centre for Endovascular Surgery, Roosevelt Hospital, Mount Sinai Health Stystem, New York, New York, USA
Johanna Fifi - Hyman Newman Institute for Neurology and Neurosurgery, Centre for Endovascular Surgery, Roosevelt Hospital, Mount Sinai Health Stystem, New York, New York, USA
Alejandro Berenstein - Hyman Newman Institute for Neurology and Neurosurgery, Centre for Endovascular Surgery, Roosevelt Hospital, Mount Sinai Health Stystem, New York, New York, USA
Resource Type: Journal article
Publication Details: Journal of neurointerventional surgery, Vol.7(6), pp.458-461
DOI: 10.1136/neurintsurg-2014-011165
PMID: 24714611
NLM abbreviation: J Neurointerv Surg
ISSN: 1759-8478
eISSN: 1759-8486
Publisher: England
Language: English
Date published: 06/2015
Academic Unit: Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9984020654102771

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