NANETS/SNMMI Procedure Standard for Somatostatin Receptor-Based Peptide Receptor Radionuclide Therapy with Lu-177-DOTATATE

Thomas A. Hope; Amanda Abbott; Karen Colucci; David L. Bushnell; Linda Gardner; William S. Graham; Sheila Lindsay; David C. Metz; Daniel A. Pryma; Michael G. Stabin; Jonathan R. Strosberg

doi:10.2967/jnumed.118.230607

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NANETS/SNMMI Procedure Standard for Somatostatin Receptor-Based Peptide Receptor Radionuclide Therapy with Lu-177-DOTATATE

Journal article

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NANETS/SNMMI Procedure Standard for Somatostatin Receptor-Based Peptide Receptor Radionuclide Therapy with Lu-177-DOTATATE

Thomas A. Hope, Amanda Abbott, Karen Colucci, David L. Bushnell, Linda Gardner, William S. Graham, Sheila Lindsay, David C. Metz, Daniel A. Pryma, Michael G. Stabin, …

The Journal of nuclear medicine (1978), Vol.60(7), pp.937-943

07/01/2019

DOI: 10.2967/jnumed.118.230607

PMID: 31263080

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Abstract

With the recent approval of Lu-177-DOTATATE for use in gastroen-teropancreatic neuroendocrine tumors, access to peptide receptor radionuclide therapy is increasing. Representatives from the North American Neuroendocrine Tumor Society and the Society of Nuclear Medicine and Molecular Imaging collaborated to develop a practical consensus guideline for the administration of Lu-177-DOTATATE. In this paper, we discuss patient screening, maintenance somatostatin analog therapy requirements, treatment location and room preparation, drug administration, and patient release as well as strategies for radiation safety, toxicity monitoring, management of potential complications, and follow-up. Controversies regarding the role of radiation dosimetry are discussed as well. This document is designed to provide practical guidance on how to safely treat patients with this therapy.

Life Sciences & Biomedicine

Radiology, Nuclear Medicine & Medical Imaging

Science & Technology

Details

Title: Subtitle: NANETS/SNMMI Procedure Standard for Somatostatin Receptor-Based Peptide Receptor Radionuclide Therapy with Lu-177-DOTATATE
Creators: Thomas A. Hope - University of California, San Francisco
Amanda Abbott - Dana-Farber Cancer Institute
Karen Colucci - Lehigh Valley Hospital-Pocono
David L. Bushnell - Roy J. and Lucille A. Carver College of Medicine
Linda Gardner - University of California, Los Angeles
William S. Graham - University of California, San Francisco
Sheila Lindsay - University of California, San Francisco
David C. Metz - University of Pennsylvania
Daniel A. Pryma - University of Pennsylvania
Michael G. Stabin - NV5/Dade Moeller, Richland, Washington; and.
Jonathan R. Strosberg - Moffitt Cancer Center
Resource Type: Journal article
Publication Details: The Journal of nuclear medicine (1978), Vol.60(7), pp.937-943
DOI: 10.2967/jnumed.118.230607
PMID: 31263080
NLM abbreviation: J Nucl Med
ISSN: 0161-5505
eISSN: 1535-5667
Publisher: Soc Nuclear Medicine Inc
Number of pages: 7
Grant note: P30CA086862 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) P30 CA086862; P50 CA174521 / NCI NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
Language: English
Date published: 07/01/2019
Academic Unit: Radiology
Record Identifier: 9984318696802771

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