Journal article
Naloxone Reversal of Diazepam Effects
Anesthesiology (Philadelphia), Vol.53(3), pp.264-264
09/01/1980
DOI: 10.1097/00000542-198009000-00024
PMID: 7425345
Abstract
Christensen and Huttel are to be commended for their carefully designed and conducted study of the effects of naloxone on diazepam-induced sedation. Unfortunately, they did not report the mean consciousness scores for the naloxone and placebo groups, but simply stated that 'statistical analysis showed no difference (P = 0.02).' I cannot understand why Drs. Christensen and Huttel have concluded that there was 'no difference', since the P value of 0.02 indicates a 98 per cent probability that whatever difference existed between the mean consciousness scores did not occur by chance. If their studies showed a greater mean consciousness score in the naloxone-treated group, with P = 0.02, I would interpret that to indicate an incomplete, but detectable, effect of naloxone in reversing diazepam-induced sedation.
Details
- Title: Subtitle
- Naloxone Reversal of Diazepam Effects
- Creators
- Edward F. Bell
- Resource Type
- Journal article
- Publication Details
- Anesthesiology (Philadelphia), Vol.53(3), pp.264-264
- DOI
- 10.1097/00000542-198009000-00024
- PMID
- 7425345
- NLM abbreviation
- Anesthesiology
- ISSN
- 0003-3022
- eISSN
- 1528-1175
- Language
- English
- Date published
- 09/01/1980
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984353846802771
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