Journal article
Narrative review on potential role of gut microbiota in certain substance addiction
Progress in neuro-psychopharmacology & biological psychiatry, Vol.106, pp.110093-110093
03/02/2021
DOI: 10.1016/j.pnpbp.2020.110093
PMID: 32898589
Abstract
As a neuropsychiatric disorder, substance addiction represents a major public health issue with high prevalence and mortality in many countries. Recently, gut microbiota has been certified to play a part in substance addiction through various mechanisms. Hence, we mainly focused on three substance including alcohol, cocaine and methamphetamine in this review, and summarized their relationships with gut microbiota, respectively. Besides, we also concluded the possible treatments for substance addiction from the perspective of applying gut microbiota. This review aims to build a bridge between substance addiction and gut microbiota according to existing evidences, so as to excavate the possible bi-directional function of microbiota-gut-brain axis in substance addiction for developing therapeutic strategies in the future.
•Substance addiction is a severe public health problem in many countries.•Substance addiction and gut microbiota are closely related.•Treatments involving gut microbiota are promising for substance addiction.
Details
- Title: Subtitle
- Narrative review on potential role of gut microbiota in certain substance addiction
- Creators
- Chenyuan Qin - Huazhong University of Science and TechnologyJiawei Hu - Huazhong University of Science and TechnologyYiming Wan - Huazhong University of Science and TechnologyMengyao Cai - Huazhong University of Science and TechnologyZhenting Wang - Huazhong University of Science and TechnologyZhao Peng - Huazhong University of Science and TechnologyYuxiao Liao - Huazhong University of Science and TechnologyDan Li - Huazhong University of Science and TechnologyPing Yao - Huazhong University of Science and TechnologyLiegang Liu - Huazhong University of Science and TechnologyShuang Rong - Huazhong University of Science and TechnologyWei Bao - University of IowaGuifeng Xu - University of IowaWei Yang - Huazhong University of Science and Technology
- Resource Type
- Journal article
- Publication Details
- Progress in neuro-psychopharmacology & biological psychiatry, Vol.106, pp.110093-110093
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.pnpbp.2020.110093
- PMID
- 32898589
- ISSN
- 0278-5846
- eISSN
- 1878-4216
- Grant note
- DOI: 10.13039/501100012166, name: National Key Research and Development Program of China, award: 2018YFC1603100; DOI: 10.13039/501100001809, name: National Natural Science Foundation of China, award: NSFC81502811; DOI: 10.13039/501100003819, name: Natural Science Foundation of Hubei Province, award: ZRMS2017000504; name: Hubei Province Health and Family Planning Scientific Research Project, award: WJ2019M114; DOI: 10.13039/501100012166, name: National Key Research and Development Program of China, award: 2018YFC1603100; DOI: 10.13039/501100001809, name: National Natural Science Foundation of China, award: NSFC81502811; DOI: 10.13039/501100003819, name: Natural Science Foundation of Hubei Province, award: ZRMS2017000504; name: Hubei Province Health and Family Planning Scientific Research Project, award: WJ2019M114
- Language
- English
- Date published
- 03/02/2021
- Academic Unit
- Stead Family Department of Pediatrics
- Record Identifier
- 9984364658502771
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