National Institutes of Health Consensus Development Conference Statement on Cervical Cancer

P.S. Braly; A.S. Lichter; D.K. Ash; J.L. Bader; R.S. Berkowitz; J.M. Cain; A.M. Fremgen; I. Gage; J.S. Hutchison; D.C. Ihde; Audrey F Saftlas; P.E. Saigo; R.L. Sweet; B.L. Andersen; Jo Ann Benda; C.L. Brown; Gary Lee Eddy Sr; P.J. Eifel; P.W. Grigsby; K.D. Hatch; M.R. Henry; R. Herrero; A.E. Howes; D. Kapp; H.M. Keys; R.M. Lanciano; D. Lowy; J.F. Magrina; M.F. Mitchell; M. Morris; G.A. Omura; J. Overgaard; M.A. Penalver; D.G. Petereit; M.E. Randall; A.H. Rusell; William J Spanos Jr; F.B. Stehman; M.A. Steller; M.H.N. Tattersall; G.M. Thomas; J.M. Elliott; A.H. Epstein; J.H. Ferguson; W.H. Hall; P.J. Hitchcock; C.P. Hunter; B.S. Kramer; H.W. Lawson; J.R. Lunney; C. McNeil; N. Munoz; C. Nichols; R.C. Park; V.W. Pinn; J. Ruffin; S. Scherr

doi:10.1006/gyno.1997.4849

Back

National Institutes of Health Consensus Development Conference Statement on Cervical Cancer

Journal article

Peer reviewed

National Institutes of Health Consensus Development Conference Statement on Cervical Cancer

P.S. Braly, A.S. Lichter, D.K. Ash, J.L. Bader, R.S. Berkowitz, J.M. Cain, A.M. Fremgen, I. Gage, J.S. Hutchison, D.C. Ihde, …

Gynecologic oncology, Vol.66(3), pp.351-361

09/01/1997

DOI: 10.1006/gyno.1997.4849

View Online

Abstract

Objective.To provide physicians and the general public with a responsible assessment of current screening, prevention, and treatment approaches to cervical cancer. Participants.The participants were a non-Federal, nonadvocate, 13-member panel representing the fields of obstetrics and gynecology, gynecologic oncology, radiation oncology, and epidemiology. In addition, 28 experts in obstetrics and gynecology, gynecologic oncology, radiation oncology, gynecologic surgery, and psychology presented data to the panel and a conference audience of 500. Evidence.The literature was searched through Medline and an extensive bibliography of references was provided to the panel and the conference audience. Experts prepared abstracts with relevant citations from the literature. Scientific evidence was given precedence over clinical anecdotal experience. Consensus process.The panel, answering predefined questions, developed their conclusions based on the scientific evidence presented in open forum and the scientific literature. The panel composed a draft statement that was read in its entirety and circulated to the experts and the audience for comment. Thereafter, the panel resolved conflicting recommendations and released a revised statement at the end of the conference. The panel finalized the revisions within a few weeks after the conference. Conclusions.Carcinoma of the cervix is causally related to infection with the human papillomavirus (HPV). Reducing the rate of HPV infection by changes in sexual behaviors in young people and/or through the development of an effective HPV vaccine would reduce the incidence of this disease. Pap smear screening remains the best available method of reducing the incidence and mortality of invasive cervical cancer. Persons with stage IA1 disease have a high cure rate with either simple hysterectomy or, where fertility preservation is an issue, by cone biopsy with clear margins. For patients with stage I and stage IIA disease, radical surgery and radiation are equally effective treatments. These patients should be carefully selected to receive one treatment or the other, but not both, as their combined use substantially increases the cost and morbidity of treatment. Women with more advanced, nonmetastatic disease should be treated with radiation. Recurrent cervical cancer confined to the pelvis should be treated with the modality not previously received. Radiation is recommended to palliate symptoms in patients with metastatic disease. Article Note: (footnote) ☆NIH Consensus Statements are prepared by a nonadvocate, non-Federal panel of experts, based on (1) presentations by investigators working in areas relevant to the consensus questions during a 2-day public session, (2) questions and statements from conference attendees during open discussion periods that are part of the public session, and (3) closed deliberations by the panel during the remainder of the second day and morning of the third. This statement is an independent report of the panel and is not a policy statement of the NIH or the Federal Government.

Cervical Cancer

Conferences and conventions

Conferences, meetings and seminars

Health aspects

Papillomavirus infections

Women

Details

Title: Subtitle: National Institutes of Health Consensus Development Conference Statement on Cervical Cancer
Creators: P.S. Braly - University Medical Center New Orleans
A.S. Lichter - University Medical Center New Orleans
D.K. Ash - University Medical Center New Orleans
J.L. Bader - University Medical Center New Orleans
R.S. Berkowitz - University Medical Center New Orleans
J.M. Cain - University Medical Center New Orleans
A.M. Fremgen - University Medical Center New Orleans
I. Gage - University Medical Center New Orleans
J.S. Hutchison - University Medical Center New Orleans
D.C. Ihde - University Medical Center New Orleans
Audrey F Saftlas - University Medical Center New Orleans
P.E. Saigo - University Medical Center New Orleans
R.L. Sweet - University Medical Center New Orleans
B.L. Andersen - University Medical Center New Orleans
Jo Ann Benda - University Medical Center New Orleans
C.L. Brown - Section of Gynecologic Oncology, Department of Obstetrics/Gynecology, Louisiana State Univ. Medical Center
Gary Lee Eddy Sr - Section of Gynecologic Oncology, Department of Obstetrics/Gynecology, Louisiana State Univ. Medical Center
P.J. Eifel - University Medical Center New Orleans
P.W. Grigsby - University Medical Center New Orleans
K.D. Hatch - University Medical Center New Orleans
M.R. Henry - University Medical Center New Orleans
R. Herrero - University Medical Center New Orleans
A.E. Howes - University Medical Center New Orleans
D. Kapp - University Medical Center New Orleans
H.M. Keys - University Medical Center New Orleans
R.M. Lanciano - University Medical Center New Orleans
D. Lowy - University Medical Center New Orleans
J.F. Magrina - University Medical Center New Orleans
M.F. Mitchell - Section of Gynecologic Oncology, Department of Obstetrics/Gynecology, Louisiana State Univ. Medical Center
M. Morris - University Medical Center New Orleans
G.A. Omura - University Medical Center New Orleans
J. Overgaard - University Medical Center New Orleans
M.A. Penalver - University Medical Center New Orleans
D.G. Petereit - University Medical Center New Orleans
M.E. Randall - University Medical Center New Orleans
A.H. Rusell - University Medical Center New Orleans
William J Spanos Jr - Section of Gynecologic Oncology, Department of Obstetrics/Gynecology, Louisiana State Univ. Medical Center
F.B. Stehman - University Medical Center New Orleans
M.A. Steller - University Medical Center New Orleans
M.H.N. Tattersall - University Medical Center New Orleans
G.M. Thomas - Section of Gynecologic Oncology, Department of Obstetrics/Gynecology, Louisiana State Univ. Medical Center
J.M. Elliott - University Medical Center New Orleans
A.H. Epstein - Section of Gynecologic Oncology, Department of Obstetrics/Gynecology, Louisiana State Univ. Medical Center
J.H. Ferguson - University Medical Center New Orleans
W.H. Hall - University Medical Center New Orleans
P.J. Hitchcock - University Medical Center New Orleans
C.P. Hunter - University Medical Center New Orleans
B.S. Kramer - University Medical Center New Orleans
H.W. Lawson - University Medical Center New Orleans
J.R. Lunney - University Medical Center New Orleans
C. McNeil - University Medical Center New Orleans
N. Munoz - University Medical Center New Orleans
C. Nichols - University Medical Center New Orleans
R.C. Park - Section of Gynecologic Oncology, Department of Obstetrics/Gynecology, Louisiana State Univ. Medical Center
V.W. Pinn - University Medical Center New Orleans
J. Ruffin - University Medical Center New Orleans
S. Scherr - University Medical Center New Orleans
Resource Type: Journal article
Publication Details: Gynecologic oncology, Vol.66(3), pp.351-361
Publisher: Elsevier B.V
DOI: 10.1006/gyno.1997.4849
ISSN: 0090-8258
eISSN: 1095-6859
Language: English
Date published: 09/01/1997
Description audience: Academic
Academic Unit: Pathology; Epidemiology
Record Identifier: 9984363620902771

Metrics

5 Record Views