Natural history of Huntington disease

E Ray Dorsey; Christopher A Beck; Kristin Darwin; Paige Nichols; Alicia F D Brocht; Kevin M Biglan; Ira Shoulson; Huntington Study Group COHORT Investigators

doi:10.1001/jamaneurol.2013.4408

Back

Journal article

Open access

Peer reviewed

Natural history of Huntington disease

E Ray Dorsey, Christopher A Beck, Kristin Darwin, Paige Nichols, Alicia F D Brocht, Kevin M Biglan, Ira Shoulson and Huntington Study Group COHORT Investigators

JAMA neurology, Vol.70(12), pp.1520-1530

12/2013

DOI: 10.1001/jamaneurol.2013.4408

PMID: 24126537

Files and links (1)

url

https://doi.org/10.1001/jamaneurol.2013.4408View

Published (Version of record) Open Access

Abstract

Understanding the natural history of Huntington disease will inform patients and clinicians on the disease course and researchers on the design of clinical trials.

Australia

Canada

United States

Disability Evaluation

Severity of Illness Index

Humans

Middle Aged

Male

Trinucleotide Repeats - genetics

Nerve Tissue Proteins - genetics

Disease Progression

Huntington Disease - complications

Huntingtin Protein

Cognition Disorders - etiology

Movement Disorders - etiology

Adult

Female

Aged

Retrospective Studies

Mental Disorders - etiology

Cohort Studies

Details

Title: Subtitle: Natural history of Huntington disease
Creators: E Ray Dorsey - Department of Neurology, Johns Hopkins Medicine, Baltimore, Maryland6now with the University of Rochester Medical Center, Rochester, New York
Christopher A Beck - Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, New York
Kristin Darwin - Department of Neurology, Johns Hopkins Medicine, Baltimore, Maryland
Paige Nichols - Department of Neurology, Johns Hopkins Medicine, Baltimore, Maryland
Alicia F D Brocht - Center for Human Experimental Therapeutics, University of Rochester Medical Center, Rochester, New York
Kevin M Biglan - Department of Neurology, University of Rochester Medical Center, Rochester, New York
Ira Shoulson - Department of Neurology, Georgetown University Medical Center, Washington, DC
Huntington Study Group COHORT Investigators
Contributors: Ergun Y Uc (Contributor) - University of Iowa, Neurology
Resource Type: Journal article
Publication Details: JAMA neurology, Vol.70(12), pp.1520-1530
DOI: 10.1001/jamaneurol.2013.4408
PMID: 24126537
NLM abbreviation: JAMA Neurol
ISSN: 2168-6149
eISSN: 2168-6157
Publisher: United States
Language: English
Date published: 12/2013
Academic Unit: Neurology
Record Identifier: 9984020871702771

Metrics

33 Record Views

104 Times Cited - Web of Science