Necrotizing enterovirus myositis in a pediatric renal transplant recipient

Kristen G. Valencia Deray; Margaret G. Taylor; Melissa M. Blessing; Claire E. Bocchini; Erica K. Schallert; Daniel Ruderfer; Poyyapakkam R. Srivaths; Rossana Malatesta Muncher

doi:10.1111/petr.14275

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Necrotizing enterovirus myositis in a pediatric renal transplant recipient

Journal article

Peer reviewed

Necrotizing enterovirus myositis in a pediatric renal transplant recipient

Kristen G. Valencia Deray, Margaret G. Taylor, Melissa M. Blessing, Claire E. Bocchini, Erica K. Schallert, Daniel Ruderfer, Poyyapakkam R. Srivaths and Rossana Malatesta Muncher

Pediatric transplantation, Vol.26(5), pp.e14275-n/a

08/2022

DOI: 10.1111/petr.14275

PMID: 35340121

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Abstract

Background Enteroviruses can cause severe infections, including viral myocarditis, meningitis, acute flaccid myelitis, and viral myositis. Methods/Results We report a 3-year-old female renal transplant recipient who presented to a tertiary care hospital with elevated serum liver aminotransferases and subsequently developed proximal muscle pain, weakness, and respiratory distress during the first week of hospitalization. Imaging of the lower extremities revealed diffuse myositis of the proximal thigh and pelvic muscles. A muscle biopsy was obtained and revealed necrotizing myositis with immunostaining positive for enterovirus, consistent with a diagnosis of enterovirus necrotizing myositis. She had complete resolution of symptoms with steroids, intravenous immune globulin, reduced tacrolimus dose, and physical therapy. Conclusions Enterovirus myositis should be included in the differential diagnosis for necrotizing myositis following renal transplantation in children.

Life Sciences & Biomedicine

Pediatrics

Science & Technology

Transplantation

Details

Title: Subtitle: Necrotizing enterovirus myositis in a pediatric renal transplant recipient
Creators: Kristen G. Valencia Deray - Baylor College of Medicine
Margaret G. Taylor - Baylor College of Medicine
Melissa M. Blessing - Baylor College of Medicine
Claire E. Bocchini - Baylor College of Medicine
Erica K. Schallert - Texas Children's Hospital
Daniel Ruderfer - Baylor College of Medicine
Poyyapakkam R. Srivaths - Baylor College of Medicine
Rossana Malatesta Muncher - Baylor College of Medicine
Resource Type: Journal article
Publication Details: Pediatric transplantation, Vol.26(5), pp.e14275-n/a
Publisher: Wiley
DOI: 10.1111/petr.14275
PMID: 35340121
ISSN: 1397-3142
eISSN: 1399-3046
Number of pages: 4
Language: English
Date published: 08/2022
Academic Unit: Pathology
Record Identifier: 9984756263402771

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