Journal article
Nephrogenic Diabetes Insipidus Due to Urinary Tract Obstruction: A Systematic Review
Internal Medicine and Medical Investigation Journal, Vol.2(4), p.113
10/05/2017
DOI: 10.24200/imminv.v2i4.110
Abstract
Background: Nephrogenic diabetes insipidus (NDI) due to obstructive uropathy is not widely known by physicians and hence not well represented in the literature. To better understand its presentation, clinical course, and available treatments, we conducted a systematic review of case reports on NDI due to urinary tract obstruction.Methods: This observational study was a systematic review of 19 human cases found in the literature. It was done retrospectively to focus on whether NDI can occur due to obstruction of the urinary tract and, if so, what the mechanism (pathophysiology) is.Results: We found that the most common symptom of NDI due to urinary tract obstruction was polyuria. The most common cause of NDI due to urinary tract obstruction was cancer. The most common site for obstruction was the ureter. And the most common test used to confirm the diagnosis was failure to concentrate urine after the administration of desmopressin. Surgical intervention was the most common treatment to relieve obstruction.Conclusion: We found that urinary tract obstruction can cause NDI. With early diagnosis and timely relief of the obstruction, NDI can be reversible.
Details
- Title: Subtitle
- Nephrogenic Diabetes Insipidus Due to Urinary Tract Obstruction: A Systematic Review
- Creators
- Mohammad Ali Raza QizalbashRida ZahraAbhinav KumarAdnan AdilKamran KhanSayed Tauseef Ahmad JanShazia ShahShristi ShresthaAyeshah SarfarazAmandeep SinghHamdan Gul
- Resource Type
- Journal article
- Publication Details
- Internal Medicine and Medical Investigation Journal, Vol.2(4), p.113
- DOI
- 10.24200/imminv.v2i4.110
- ISSN
- 2474-7750
- eISSN
- 2474-7750
- Language
- English
- Date published
- 10/05/2017
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984695809702771
Metrics
32 Record Views