Journal article
NetPath: a public resource of curated signal transduction pathways
GenomeBiology.com, Vol.11(1), pp.R3-R3
2010
DOI: 10.1186/gb-2010-11-1-r3
PMCID: PMC2847715
PMID: 20067622
Abstract
NetPath, a novel community resource of curated human signaling pathways is presented and its utility demonstrated using immune signaling data.
We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include approximately 1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches.
Details
- Title: Subtitle
- NetPath: a public resource of curated signal transduction pathways
- Creators
- Kumaran Kandasamy - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaS Sujatha Mohan - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaRajesh Raju - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaShivakumar Keerthikumar - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaGhantasala S Sameer Kumar - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaAbhilash K Venugopal - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaDeepthi Telikicherla - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaJ Daniel Navarro - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaSuresh Mathivanan - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaChristian Pecquet - Current address: Research Unit for Immunoinformatics, RIKEN Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Kanagawa 230-0045, JapanSashi Kanth Gollapudi - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaSudhir Gopal Tattikota - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaShyam Mohan - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaHariprasad Padhukasahasram - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaYashwanth Subbannayya - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaRenu Goel - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaHarrys KC Jacob - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaJun Zhong - McKusick-Nathans Institute of Genetic Medicine and the Department of Biological Chemistry, Johns Hopkins University, Baltimore, Maryland 21205, USARaja Sekhar - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaVishalakshi Nanjappa - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaLavanya Balakrishnan - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaRoopashree Subbaiah - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaY L Ramachandra - Department of Biotechnology and Bioinformatics, Kuvempu University, Jnanasahyadri, Shimoga 577451, IndiaB Abdul Rahiman - Department of Biotechnology and Bioinformatics, Kuvempu University, Jnanasahyadri, Shimoga 577451, IndiaTS Keshava Prasad - Institute of Bioinformatics, International Tech Park, Bangalore 560066, IndiaJian-Xin Lin - Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USAJon CD Houtman - Department of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USAStephen Desiderio - Department of Molecular Biology and Genetics, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USAJean-Christophe Renauld - The Ludwig Institute for Cancer Research, Brussels Branch, and the Experimental Medicine Unit, Christian de Duve Institute of Cellular Pathology, Universite Catholique de Louvain, avenue Hippocrate 74, B-1200-Brussels, BelgiumStefan N Constantinescu - The Ludwig Institute for Cancer Research, Brussels Branch, and the Experimental Medicine Unit, Christian de Duve Institute of Cellular Pathology, Universite Catholique de Louvain, avenue Hippocrate 74, B-1200-Brussels, BelgiumOsamu Ohara - Laboratory for Immunogenomics, RIKEN Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Kanagawa 230-0045, JapanToshio Hirano - Laboratory for Cytokine Signaling, RIKEN Research Center for Allergy and Immunology, Yokohama, Kanagawa 230-0045, JapanMasato Kubo - Research Institute for Biological Sciences, Tokyo University of Science, Yamazaki, Noda City, Chiba 278-0022, JapanSujay Singh - IMGENEX India Pvt. Ltd., Bhubaneswar, Orissa 92121, IndiaPurvesh Khatri - Department of Computer Science, Wayne State University, Detroit, Michigan 48202, USASorin Draghici - Department of Computer Science, Wayne State University, Detroit, Michigan 48202, USAGary D Bader - Banting and Best Department of Medical Research, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College St, Toronto, Ontario M5S 3E1, CanadaChris Sander - Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USAWarren J Leonard - Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USAAkhilesh Pandey - McKusick-Nathans Institute of Genetic Medicine and the Department of Biological Chemistry, Johns Hopkins University, Baltimore, Maryland 21205, USA
- Resource Type
- Journal article
- Publication Details
- GenomeBiology.com, Vol.11(1), pp.R3-R3
- DOI
- 10.1186/gb-2010-11-1-r3
- PMID
- 20067622
- PMCID
- PMC2847715
- NLM abbreviation
- Genome Biol
- ISSN
- 1465-6906
- eISSN
- 1465-6914
- Publisher
- BioMed Central
- Language
- English
- Date published
- 2010
- Academic Unit
- Microbiology and Immunology; Internal Medicine
- Record Identifier
- 9984094545002771
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