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Neu-Laxova syndrome: A case report and review of the literature
Journal article   Open access   Peer reviewed

Neu-Laxova syndrome: A case report and review of the literature

M. Ugras, G. Kocak and H. Ozcan
Journal of the European Academy of Dermatology and Venereology, Vol.20(9), pp.1126-1128
10/2006
DOI: 10.1111/j.1468-3083.2006.01645.x
PMID: 16987270
url
https://doi.org/10.1111/j.1468-3083.2006.01645.xView
Published (Version of record) Open Access

Abstract

Neu–Laxova syndrome (NLS) is a rare autosomal recessive syndrome, characterized by severe intrauterine growth retardation (IUGR), microcephaly, abnormal brain development, oedema and ichthyosis. It was first reported in 1971 by Neu et al. (Pediatrics 47: 610–612) and since then no more than 60 cases have been reported. A newborn girl delivered from a 29-year-old healthy mother was admitted to hospital with a thick membrane covering her body and dismorphic appearance. The diagnosis of NLS was made according to characteristic features. The syndrome is known to have a poor prognosis and the baby lived for 9 weeks. This case is one of the longest living cases of NLS and the fourth case reported from Turkey.
Growth retardation Ichthyosis Neu-Laxova syndrome

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