Logo image
Neural-Tube Defects in a Prehistoric Southwestern Indian Population
Journal article   Open access   Peer reviewed

Neural-Tube Defects in a Prehistoric Southwestern Indian Population

Eric J. Devor and L. S. Cordell
Annals of Human Biology, Vol.8(1), pp.65-75
01/01/1981
DOI: 10.1080/03014468100004801
url
https://doi.org/10.1080/03014468100004801View
Published (Version of record) Open Access

Abstract

Concern with the frequency and patterning of the occurrence of midline neural-tube defects among contemporary human populations is widespread. These defects are, however, quite old and occur in unusually high numbers of prehistoric skeletons. A common explanation offered for such high incidence has been inbreeding among small, reproductively isolated populations. In a sample of 54 skeletons from the prehistoric south-western Indian site of Tijeras Pueblo in New Mexico, failure of neural-tube closure occurs in 10% of sacra recovered. While a more homogeneous genetic background and inbreeding may account for a portion of this elevated prevalence, the cause appears to lie with cultural-environmental factors. It is suggested that the aetiology of these conditions has become more complex in recent human history. © 1981 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
Obstetrics and Gynecology

Details

Metrics

Logo image