Neural evidence that conscious awareness of errors is reduced in depression following a traumatic brain injury

N. W. Bailey; K. E. Hoy; J. J. Maller; D. J. Upton; R. A. Segrave; B. M. Fitzgibbon; P. B. Fitzgerald

doi:10.1016/j.biopsycho.2015.01.011

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Neural evidence that conscious awareness of errors is reduced in depression following a traumatic brain injury

Journal article

Peer reviewed

Neural evidence that conscious awareness of errors is reduced in depression following a traumatic brain injury

N. W. Bailey, K. E. Hoy, J. J. Maller, D. J. Upton, R. A. Segrave, B. M. Fitzgibbon and P. B. Fitzgerald

Biological psychology, Vol.106, pp.1-10

03/01/2015

DOI: 10.1016/j.biopsycho.2015.01.011

PMID: 25637786

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Abstract

Impaired error awareness is related to poorer outcome following traumatic brain injury (TBI). Error awareness deficits are also found in major depressive disorder (MDD), but have not been examined in the MDD that follows a TBI (TBI-MDD). This study assessed neural activity related to error awareness in TBI-MDD. Four groups completed a response inhibition task while EEG was recorded-healthy controls (N=15), MDD-only (N=15), TBI-only (N=16), and TBI-MDD (N=12). Error related EEG activity was compared using powerful randomisation statistics that included all electrodes and time points. Participants with TBI-MDD displayed less frontally distributed neural activity, suggesting reduced contribution from frontal generating sources. Neural activity during this time window is thought to reflect conscious awareness of errors. The TBI-only and MDD-only groups did not differ from controls, and early error processing was unaffected, suggesting early error detection is intact. (C) 2015 Elsevier B.V. All rights reserved.

Behavioral Sciences

Life Sciences & Biomedicine

Psychology

Psychology, Biological

Psychology, Experimental

Science & Technology

Social Sciences

Details

Title: Subtitle: Neural evidence that conscious awareness of errors is reduced in depression following a traumatic brain injury
Creators: N. W. Bailey - Monash Alfred Psychiatry Research centre
K. E. Hoy - Monash Alfred Psychiatry Research centre
J. J. Maller - Monash Alfred Psychiatry Research centre
D. J. Upton - Australian Psychological Society
R. A. Segrave - Monash Alfred Psychiatry Research centre
B. M. Fitzgibbon - Monash University
P. B. Fitzgerald - Monash Alfred Psychiatry Research centre
Resource Type: Journal article
Publication Details: Biological psychology, Vol.106, pp.1-10
DOI: 10.1016/j.biopsycho.2015.01.011
PMID: 25637786
NLM abbreviation: Biol Psychol
ISSN: 0301-0511
eISSN: 1873-6246
Publisher: Elsevier
Number of pages: 10
Grant note: D082 / Victorian Neurotrauma Initiative 546229; APP1013686; GNT1070073 / NHMRC; National Health & Medical Research Council (NHMRC) of Australia NHMRC 606907 / National Health and Medical Research Council; National Health & Medical Research Council (NHMRC) of Australia Monash University
Language: English
Date published: 03/01/2015
Academic Unit: Radiology
Record Identifier: 9984848510102771

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