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Neuraxial labor analgesia in a parturient with carnitine palmitoyl transferase type II deficiency: a case report
Journal article   Open access   Peer reviewed

Neuraxial labor analgesia in a parturient with carnitine palmitoyl transferase type II deficiency: a case report

Taylor K. Bowman, Adeeb Oweidat, Nour El Hage Chehade, Monica Cheriyan, Sabry Ayad and McCallum Hoyt
International journal of obstetric anesthesia, Vol.60, 104246
11/2024
DOI: 10.1016/j.ijoa.2024.104246
PMID: 39209572
url
https://doi.org/10.1016/j.ijoa.2024.104246View
Published (Version of record) Open Access

Abstract

Carnitine Palmitoyl Transferase Type II (CPT II) deficiency is a disorder of fatty acid beta oxidation that causes decreased adenosine triphosphate (ATP) and ketone production during periods of fasting or high energy requirements. Labor and delivery can precipitate attacks for parturients with this disorder, causing hypoglycemia, muscle weakness, rhabdomyolysis, and kidney failure. Anesthetic management considers the delivery mode and anesthetic medications available to reduce these risks. We present a case of a parturient with CPT II deficiency who achieved a vaginal delivery under a labor epidural analgesic. We also discuss our alternative plans had a different delivery mode been required.

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