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Neurobehavioral testing in human risk assessment
Journal article   Open access   Peer reviewed

Neurobehavioral testing in human risk assessment

Diane S Rohlman, Roberto Lucchini, W Kent Anger, David C Bellinger and Christoph van Thriel
Neurotoxicology (Park Forest South), Vol.29(3), pp.556-567
05/2008
DOI: 10.1016/j.neuro.2008.04.003
PMCID: PMC2492890
PMID: 18539229
url
https://hdl.handle.net/11380/1318804View
Open Access

Abstract

Neurobehavioral tests are being increasingly used in human risk assessment and there is a strong need for guidance. The field of neurobehavioral toxicology has evolved from research which initially focused on using traditional neuropsychological tests to identify "abnormal cases" to include methods used to detect sub-clinical deficits, to further incorporate the use of neurosensory assessment, and to expand testing from occupational populations to vulnerable populations including older adults and children. Even as exposures in the workplace are reduced, they have been increasing in the environment and research on exposure has now expanded to cross the entire lifetime. These neurobehavioral methods are applied in research and the findings used for regulatory purposes to develop preventative action for exposed populations. This paper reflects a summary of the talks presented at the Neurobehavioral Testing in Human Risk Assessment symposium presented at the 11th meeting of the International Neurotoxicology Association.
 Behavior - drug effects Effect Modifier, Epidemiologic Neurotoxicity Syndromes - psychology Risk Assessment Pesticides - toxicity Humans Adult Population Irritants - toxicity Environmental Exposure - statistics & numerical data Child Neurotoxicity Syndromes - epidemiology

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