Journal article
Neurobiobehavioral responses to virtual social rejection in females—exploring the influence of oxytocin
Social cognitive and affective neuroscience, Vol.16(3), pp.326-333
03/05/2021
DOI: 10.1093/scan/nsaa168
PMID: 33326562
Abstract
Abstract In recent years, especially adolescents and young adults interact frequently via social media and digital communication. Mimicking an online communication platform where participants could initiate short conversations with two computerized interlocutors, the Verbal Interaction Social Threat Task (VISTTA) was used to induce feelings of social rejection. Motivational and physiological reactions were investigated in 43 healthy young women undergoing functional magnetic resonance imaging (fMRI), of which 22 received 24 international units (IU) intranasal oxytocin and 21 received placebo. Replicating previous findings, social rejection entailed a lower willingness to cooperate with the two peers. Increased activation in the anterior cingulate cortex and bilateral insula/inferior frontal gyrus was observed when receiving negative feedback from others, and in the precuneus when subsequently rating one’s willingness to cooperate with them in the future. Oxytocin did not seem to alter responses to social rejection. The current findings provide validation of the VISTTA for examining consequences of rejection in a virtual social interaction that bears a strong resemblance to online communication platforms.
Details
- Title: Subtitle
- Neurobiobehavioral responses to virtual social rejection in females—exploring the influence of oxytocin
- Creators
- Sina Radke - Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH, Aachen 52074, Germany, Jülich Aachen Research Alliance (JARA) – BRAIN Institute I: Brain Structure-Function Relationships: Decoding the Human Brain at Systemic Levels, Research Center Jülich GmbH and RWTH Aachen University, Aachen 52074, GermanyKathrin Jankowiak - Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH, Aachen 52074, Germany, Research Center for Bioelectromagnetic Interaction (femu) – Institute for Occupational, Social and Environmental Medicine, University Hospital RWTH, Aachen 52074, GermanySanne Tops - Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH, Aachen 52074, GermanyTed Abel - Iowa Neuroscience Institute, Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USAUte Habel - Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH, Aachen 52074, Germany, Jülich Aachen Research Alliance (JARA) – BRAIN Institute I: Brain Structure-Function Relationships: Decoding the Human Brain at Systemic Levels, Research Center Jülich GmbH and RWTH Aachen University, Aachen 52074, GermanyBirgit Derntl - Department of Psychiatry and Psychotherapy, Medical School, University of Tübingen, Tübingen 72076, Germany
- Resource Type
- Journal article
- Publication Details
- Social cognitive and affective neuroscience, Vol.16(3), pp.326-333
- DOI
- 10.1093/scan/nsaa168
- PMID
- 33326562
- NLM abbreviation
- Soc Cogn Affect Neurosci
- ISSN
- 1749-5016
- eISSN
- 1749-5024
- Grant note
- DOI: 10.13039/501100001659, name: Deutsche Forschungsgemeinschaft, award: IRTG 2150; name: START-program, award: 691505
- Language
- English
- Date published
- 03/05/2021
- Academic Unit
- Molecular Physiology and Biophysics; Psychiatry; Psychological and Brain Sciences; Iowa Neuroscience Institute; Neuroscience and Pharmacology; Biochemistry and Molecular Biology
- Record Identifier
- 9984070735902771
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