Journal article
Neurocardiovascular regulation in mice: experimental approaches and novel findings
Clinical and experimental pharmacology & physiology, Vol.30(11), pp.885-893
11/2003
DOI: 10.1046/j.1440-1681.2003.03927.x
PMID: 14678254
Abstract
1. Neural mechanisms are of major importance in the regulation of arterial blood pressure, blood volume and other aspects of cardiovascular function. The recent explosion in gene discovery and advances in molecular technologies now provide the opportunity to define the molecular and cellular mechanisms essential to integrative neurocardiovascular regulation. The unique susceptibility of mice to genetic manipulation makes this species an attractive model for such investigation. 2. We provide here a brief overview of: (i) experimental approaches used to assess autonomic and reflex control of the circulation in mice; (ii) novel mechanisms of neurocardiovascular regulation revealed using these approaches; and (iii) findings from recent studies involving mouse models of cardiovascular disease.
Details
- Title: Subtitle
- Neurocardiovascular regulation in mice: experimental approaches and novel findings
- Creators
- Xiuying Ma - The Cardiovascular Center, The University of Iowa, Iowa City, Iowa, USAFrancois M AbboudMark W Chapleau
- Resource Type
- Journal article
- Publication Details
- Clinical and experimental pharmacology & physiology, Vol.30(11), pp.885-893
- Publisher
- Australia
- DOI
- 10.1046/j.1440-1681.2003.03927.x
- PMID
- 14678254
- ISSN
- 0305-1870
- eISSN
- 1440-1681
- Grant note
- HL14388 / NHLBI NIH HHS
- Language
- English
- Date published
- 11/2003
- Academic Unit
- Molecular Physiology and Biophysics; Cardiovascular Medicine; Fraternal Order of Eagles Diabetes Research Center; Internal Medicine
- Record Identifier
- 9984025322302771
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