Journal article
Neurodevelopmental outcomes among extremely premature infants with linear growth restriction
Journal of perinatology, Vol.39(2), pp.193-202
02/01/2019
DOI: 10.1038/s41372-018-0259-8
PMCID: PMC6351156
PMID: 30353080
Abstract
Objective To compare neurodevelopmental outcomes in linear growth-restricted (LGR) infants born <29 weeks with and without weight gain out of proportion to linear growth.
Study design We compared 2-year neurodevelopmental outcomes between infants with and without LGR and between LGR infants with and without weight gain out of proportion to linear growth. The outcomes were Bayley-III cognitive, motor, and language scores, cerebral palsy, Gross Motor Function Classification System (GMFCS) level >= 2, and neurodevelopmental impairment.
Result In total, 1227 infants were analyzed. LGR infants were smaller and less mature at birth, had higher BMI, and had lower Bayley-III language scores (82.3 vs. 85.0, p < 0.05). Among infants with LGR, infants with high BMI had lower language scores compared with those with low-to-normal BMI (80.8 vs. 83.3, p <0.05), and were more likely to have GMFCS level >= 2 and neurodevelopmental impairment.
Conclusion Among infants with LGR, weight gain out of proportion to linear growth was associated with poorer neurodevelopmental outcomes.
Details
- Title: Subtitle
- Neurodevelopmental outcomes among extremely premature infants with linear growth restriction
- Creators
- J. M. Meyers - University of RochesterS. Tan - RTI InternationalHeidi M. Harmon - Indiana UniversityE. F. Bell - University of IowaTarah T. Colaizy - University of IowaA. F. Duncan - The University of Texas Health Science Center at HoustonJane E. Brumbaugh - University of IowaR. Guillet - University of RochesterB. J. Stoll - Children's Healthcare of AtlantaC. T. D'Angio - University of RochesterMichael S. Caplan - University of ChicagoAbbot R. Laptook - Brown UniversityMartin Keszler - Brown UniversityBetty R. Vohr - Brown UniversityAngelita M. Hensman - Brown UniversityElisa Vieira - Brown UniversityEmilee Little - Brown UniversityBarbara Alksninis - Brown UniversityMary Lenore Keszler - Brown UniversityAndrea M. Knoll - Brown UniversityTheresa M. Leach - Brown UniversityElisabeth C. McGowan - Brown UniversityVictoria E. Watson - Brown UniversityMichele C. Walsh - Case Western Reserve UniversityAvroy A. Fanaroff - Case Western Reserve UniversityAnna Maria Hibbs - Case Western Reserve UniversityNancy S. Newman - Case Western Reserve UniversityAllison H. Payne - Case Western Reserve UniversityDeanne E. Wilson-Costello - Case Western Reserve UniversityBonnie S. Siner - Case Western Reserve UniversityMonika Bhola - Case Western Reserve UniversityGulgun Yalcinkaya - Case Western Reserve UniversityHarriet G. Friedman - Case Western Reserve UniversityWilliam E. Truog - University of MissouriEugenia K. Pallotto - University of MissouriHoward W. Kilbride - University of MissouriCheri Gauldin - University of MissouriAnne Holmes - University of MissouriKathy Johnson - University of MissouriAllison Knutson - University of MissouriBrenda B. Poindexter - Cincinnati Children's Hospital Medical CenterKurt Schibler - Cincinnati Children's Hospital Medical CenterBarbara Alexander - Cincinnati Children's Hospital Medical CenterCathy Grisby - Cincinnati Children's Hospital Medical CenterTeresa L. Gratton - Cincinnati Children's Hospital Medical CenterLenora Jackson - Cincinnati Children's Hospital Medical CenterKristin Kirker - Cincinnati Children's Hospital Medical CenterGreg Muthig - Cincinnati Children's Hospital Medical CenterStacey Tepe - Cincinnati Children's Hospital Medical CenterKimberly Yolton - Duke University School of MedicineRonald N. Goldberg - Duke UniversityC. Michael Cotten - Duke UniversityRich F. Goldstein - Duke UniversityWilliam F. Malcolm - Duke UniversityPatricia L. Ashley - Duke UniversityKimberley A. Fisher - Duke UniversityJoanne Finkle - Duke UniversityKathryn E. Gustafson - Duke UniversityMatthew M. Laughon - Duke UniversityCarl L. Bose - Duke UniversityJanice Bernhardt - Duke UniversityGennie Bose - Duke UniversityJanice Wereszczak - Duke UniversityDavid P. Carlton - Emory UniversityEllen C. Hale - Emory UniversityIra Adams-Chapman - Emory UniversityYvonne Loggins - Emory UniversitySheena L. Carter - Emory UniversityMaureen Mulligan LaRossa - Emory UniversityLynn C. Wineski - Emory UniversityDiane Bottcher - Emory UniversityColleen Mackie - Emory UniversityRosemary D. Higgins - Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Bethesda, MD USAStephanie Wilson Archer - Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Bethesda, MD USAGregory M. Sokol - Indiana UniversityLu-Ann Papile - Indiana UniversityAbbey C. Hines - Indiana UniversityLeslie Dawn Wilson - Indiana UniversityDianne E. Herron - Indiana UniversitySusan Gunn - Indiana UniversityLucy Smiley - Indiana UniversityKathleen A. Kennedy - The University of Texas Health Science Center at HoustonJon E. Tyson - The University of Texas Health Science Center at HoustonElizabeth Allain - The University of Texas Health Science Center at HoustonJulie Arldt-McAlister - The University of Texas Health Science Center at HoustonAllison G. Dempsey - The University of Texas Health Science Center at HoustonCarmen Garcia - The University of Texas Health Science Center at HoustonJanice John - The University of Texas Health Science Center at HoustonPatrick M. Jones - The University of Texas Health Science Center at HoustonLayne M. Lillie - The University of Texas Health Science Center at HoustonKaren Martin - The University of Texas Health Science Center at HoustonSara C. Martin - The University of Texas Health Science Center at HoustonGeorgia E. McDavid - The University of Texas Health Science Center at HoustonShawna Rodgers - The University of Texas Health Science Center at HoustonSaba Siddiki - The University of Texas Health Science Center at HoustonDaniel Sperry - The University of Texas Health Science Center at HoustonSharon L. Wright - The University of Texas Health Science Center at HoustonPablo J. Sanchez - Nationwide Childrens Hosp, Columbus, OH USALeif D. Nelin - Nationwide Childrens Hosp, Columbus, OH USASudarshan R. Jadcherla - Nationwide Childrens Hosp, Columbus, OH USAChristine A. Fortney - Nationwide Childrens Hosp, Columbus, OH USAPatricia Luzader - Nationwide Childrens Hosp, Columbus, OH USAGail E. Besner - Nationwide Childrens Hosp, Columbus, OH USANehal A. Parikh - Nationwide Childrens Hosp, Columbus, OH USAAbhik Das - RTI Int, Res Triangle Pk, NC USADennis Wallace - RTIJamie E. Newman - RTIJeanette O'Donnell Auman - RTIMargaret Crawford - RTIJenna Gabrio - RTIMarie G. Gantz - RTICarolyn M. Petrie Huitema - RTIKristin M. Zaterka-Baxter - RTIKrisa P. Van Meurs - Stanford UniversityDavid K. Stevenson - Stanford UniversitySusan R. Hintz - Stanford UniversityM. Bethany Ball - Stanford UniversityMelinda S. Proud - Stanford UniversityBarbara Bentley - Stanford UniversityMaria Elena DeAnda - Stanford UniversityAnne M. DeBattista - Stanford UniversityBeth Earhart - Stanford UniversityLynne C. Huffman - Stanford UniversityCasey E. Krueger - Stanford UniversityRyan Lucash - Stanford UniversityHali E. Weiss - Stanford UniversityWaldemar A. Carlo - University of AlabamaNamasivayam Ambalavanan - University of AlabamaMyriam Peralta-Carcelen - University of AlabamaMonica Collins - University of AlabamaShirley S. Cosby - University of AlabamaFred J. Biasini - University of AlabamaKristen C. Johnston - University of AlabamaCryshelle S. Patterson - University of AlabamaVivien A. Phillips - University of AlabamaSally Whitley - University of AlabamaUday Devaskar - Mattel Children's HospitalMeena Garg - Mattel Children's HospitalIsabell B. Purdy - Mattel Children's HospitalTeresa Chanlaw - Mattel Children's HospitalRachel Geller - Mattel Children's HospitalDan L. Ellsbury - University of IowaKaren J. Johnson - University of IowaJacky R. Walker - University of IowaDonia B. Campbell - University of IowaDiane L. Eastman - Univ Iowa, Iowa City, IA USAKristi L. Watterberg - University of New MexicoJean R. Lowe - University of New MexicoJanell F. Fuller - Univ New Mexico, Hlth Sci Ctr, Albuquerque, NM 87131 USARobin K. Ohls - University of New MexicoConra Backstrom Lacy - University of New MexicoTara Dupont - University of New MexicoElizabeth Kuan - Univ New Mexico, Hlth Sci Ctr, Albuquerque, NM 87131 USASandra Sundquist Beauman - Univ New Mexico, Hlth Sci Ctr, Albuquerque, NM 87131 USABarbara Schmidt - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USAHaresh Kirpalani - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USASara B. DeMauro - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USAAasma S. Chaudhary - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USASoraya Abbasi - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USAToni Mancini - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USAJudy C. Bernbaum - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USAMarsha Gerdes - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USAHallam Hurt - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USANoah Cook - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USADara M. Cucinotta - Univ Penn, Hosp Univ Penn, Penn Hosp, Philadelphia, PA 19104 USASatyan Lakshminrusimha - University of RochesterAnne Marie Reynolds - University of RochesterRosemary L. Jensen - University of RochesterJoan Merzbach - University of RochesterGary J. Myers - University of RochesterAshley Williams - University of RochesterKelley Yost - University of RochesterWilliam Zorn - University of RochesterKaren Wynn - University of RochesterDeanna Maffett - University of RochesterDiane Prinzing - University of RochesterJulianne Hunn - University of RochesterStephanie Guilford - University of RochesterFarooq Osman - University of RochesterMary Rowan - University of RochesterMichael G. Sacilowski - University of RochesterHolly I. M. Wadkins - University of RochesterMelissa Bowman - University of RochesterCait Fallone - University of RochesterKyle Binion - University of RochesterConstance Orme - University of RochesterAnn Marie Scorsone - University of RochesterMichelle Andrews-Hartley - University of RochesterMyra H. Wyckoff - The University of Texas Southwestern Medical CenterLuc P. Brion - The University of Texas Southwestern Medical CenterDiana M. Vasil - The University of Texas Southwestern Medical CenterLijun Chen - The University of Texas Southwestern Medical CenterRoy J. Heyne - The University of Texas Southwestern Medical CenterSally S. Adams - The University of Texas Southwestern Medical CenterElizabeth Heyne - The University of Texas Southwestern Medical CenterAlicia Guzman - The University of Texas Southwestern Medical CenterLizette E. Lee - The University of Texas Southwestern Medical CenterCatherine Twell Boatman - The University of Texas Southwestern Medical CenterSeetha Shankaran - Wayne State UniversityAthina Pappas - Wayne State UniversityGirija Natarajan - Wayne State UniversitySanjay Chawla - Wayne State UniversityMonika Bajaj - Wayne State UniversityMelissa February - Wayne State UniversityPrashant Agarwal - Wayne State UniversityKirsten Childs - Wayne State UniversityEunice Woldt - Wayne State UniversityRebecca Bara - Wayne State UniversityLaura A. Goldston - Wayne State UniversityJohn Barks - Wayne State UniversityMary Christensen - Wayne State UniversityStephanie Wiggins - Wayne State UniversityDiane White - Wayne State UniversityEunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
- Resource Type
- Journal article
- Publication Details
- Journal of perinatology, Vol.39(2), pp.193-202
- Publisher
- Springer Nature
- DOI
- 10.1038/s41372-018-0259-8
- PMID
- 30353080
- PMCID
- PMC6351156
- ISSN
- 0743-8346
- eISSN
- 1476-5543
- Number of pages
- 10
- Grant note
- National Institutes of Health, the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) U10HD068270 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) National Center for Advancing Translational Sciences (NCATS); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Advancing Translational Sciences (NCATS)
- Language
- English
- Date published
- 02/01/2019
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984353799402771
Metrics
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