Journal article
Neuroimaging Correlates of Dementia Rating Scale Performance at Baseline and 12-Month Follow-up among Patients with Vascular Dementia
Journal of geriatric psychiatry and neurology, Vol.16(4), pp.240-244
12/2003
DOI: 10.1177/0891988703258322
PMID: 14653434
Abstract
The authors previously reported that subcortical hyperintensity (SH) and whole-brain volume (WBV) each covary with different subscale scores of the Mattis Dementia Rating Scale (MDRS) among vascular dementia (VaD) patients. The present longitudinal analysis examined these relationships for change. The authors found that SH volume increased and WBV decreased significantly over 12 months. At baseline, SH volume accounted for significant variance in MDRS total score and every subscale score, except Memory. WBV was unrelated to any MDRS measure. After 12 months, SH volume was related only to the Construction subscale score, whereas WBV accounted for the majority of variance in Attention and Memory subscale performance. These findings indicate that although SH volume increases with disease progression, the relative impact of SH volume on cognitive status decreases among patients with advanced VaD.
Details
- Title: Subtitle
- Neuroimaging Correlates of Dementia Rating Scale Performance at Baseline and 12-Month Follow-up among Patients with Vascular Dementia
- Creators
- Lawrence H Sweet - Brown University Medical School, Drexel University, Neuropsychology ProgramRobert H Paul - Brown University Medical School, Drexel University, Neuropsychology ProgramRonald A Cohen - Brown University Medical School, Drexel University, Neuropsychology ProgramDavid Moser - Brown University Medical School, Drexel University, Neuropsychology ProgramBrian R Ott - Brown University Medical School, Drexel University, Neuropsychology ProgramNorman Gordon - Brown University Medical School, Drexel University, Neuropsychology ProgramJeff N Browndyke - Brown University Medical School, Drexel University, Neuropsychology ProgramPari Shah - Brown University Medical School, Drexel University, Neuropsychology ProgramKelly D Garrett - Brown University Medical School, Drexel University, Neuropsychology Program
- Resource Type
- Journal article
- Publication Details
- Journal of geriatric psychiatry and neurology, Vol.16(4), pp.240-244
- Publisher
- SAGE Publications
- DOI
- 10.1177/0891988703258322
- PMID
- 14653434
- ISSN
- 0891-9887
- eISSN
- 1552-5708
- Language
- English
- Date published
- 12/2003
- Academic Unit
- Psychiatry; Medicine Administration
- Record Identifier
- 9984003936602771
Metrics
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