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Neurologic Manifestations ofLeishmania spp.Infection
Journal article   Open access

Neurologic Manifestations ofLeishmania spp.Infection

Christine Anne Petersen and M. Heather West Greenlee
Journal of neuroparasitology, Vol.2, pp.1-5
2011
DOI: 10.4303/jnp/N110401
PMCID: PMC3110707
PMID: 21666756
url
https://doi.org/10.4303/jnp/N110401View
Published (Version of record) Open Access

Abstract

When listing common clinical signs of the spectra of Leishmania-derived diseases, neurologic malfunctions are not commonly included. Despite this, there are multiple reported instances both in human and veterinary medicine where neurologic manifestations, whether central or peripheral, are described. In this review, we describe neurologic manifestations seen during infection with Leishmania spp. with some discussion of the implicit effect of inflammation on the blood brain barrier in both medical and veterinary cases. Taken together, the material discussed here suggests that in patients from Leishmania-endemic areas, when observing neurologic symptoms, causation secondary to infection with Leishmania spp. should be highly considered.

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