Neurologic manifestations of atrial myxoma. A 12-year experience and review

L E Knepper; J Biller; H P Adams Jr; A Bruno

doi:10.1161/01.str.19.11.1435

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Neurologic manifestations of atrial myxoma. A 12-year experience and review

Journal article

Open access

Peer reviewed

Neurologic manifestations of atrial myxoma. A 12-year experience and review

L E Knepper, J Biller, H P Adams Jr and A Bruno

Stroke (1970), Vol.19(11), pp.1435-1440

11/1988

DOI: 10.1161/01.str.19.11.1435

PMID: 3188128

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https://doi.org/10.1161/01.str.19.11.1435View

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Abstract

We present the results of a 12-year retrospective analysis of 11 patients, eight women and three men, aged 16-76 years, with pathologically documented atrial myxomas. Nine of the 11 patients were found to have a left atrial myxoma; right atrial myxomas were identified in two. Five of the 11 patients (45%) had abnormalities on neurologic examination, and five of five had computed tomographic evidence of nonhemorrhagic cerebral infarction. Neurologic symptoms were the initial presentation in four patients. Six patients reported a history of cardiac disease; eight of the 11 had abnormalities on cardiac auscultation. Echocardiography in 10 patients was diagnostic in all but one. Gated magnetic resonance imaging of the heart in two patients demonstrated myxoma position and movement. Follow-up examinations (varying from 1 month to 7 years after tumor resection) in nine of 11 patients demonstrated no recurrent neurologic symptoms. Cerebral infarction is a common complication of atrial myxomas and may be the presenting feature. Recurrent cerebral emboli before surgery is not uncommon. Cardiac auscultation may be normal, and electrocardiographic changes are often nonspecific. Delayed neurologic events following surgery are rare.

Magnetic Resonance Imaging

Echocardiography

Myxoma - diagnosis

Heart Atria

Humans

Middle Aged

Male

Tomography, X-Ray Computed

Heart Neoplasms - diagnosis

Heart Neoplasms - complications

Cerebral Infarction - complications

Myxoma - complications

Cerebral Infarction - diagnostic imaging

Cerebral Angiography

Heart Neoplasms - surgery

Myxoma - surgery

Adolescent

Nervous System Diseases - etiology

Adult

Female

Aged

Retrospective Studies

Details

Title: Subtitle: Neurologic manifestations of atrial myxoma. A 12-year experience and review
Creators: L E Knepper - Department of Neurology, University of Iowa College of Medicine, Iowa City 52242
J Biller
H P Adams Jr
A Bruno
Resource Type: Journal article
Publication Details: Stroke (1970), Vol.19(11), pp.1435-1440
Publisher: United States
DOI: 10.1161/01.str.19.11.1435
PMID: 3188128
ISSN: 0039-2499
eISSN: 1524-4628
Language: English
Date published: 11/1988
Academic Unit: Neurology; Iowa Neuroscience Institute
Record Identifier: 9984020882902771

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