Journal article
Neurological injury following peripheral nerve blocks: a narrative review of estimates of risks and the influence of ultrasound guidance
Regional Anesthesia and Pain Medicine, Vol.49(2), pp.122-132
02/2024
DOI: 10.1136/rapm-2023-104855
PMID: 37940348
Abstract
BackgroundPeripheral nerve injury or post-block neurological dysfunction (PBND) are uncommon but a recognized complications of peripheral nerve blocks (PNB). A broad range of its incidence is noted in the literature and hence a critical appraisal of its occurrence is needed.ObjectiveIn this review, we wanted to know the pooled estimates of PBND and further, determine its pooled estimates following various PNB over time. Additionally, we also sought to estimate the incidence of PBND with or without US guidance.Evidence reviewA literature search was conducted in six databases. For the purposes of the review, we defined PBND as any new-onset sensorimotor disturbances in the distribution of the performed PNB either attributable to the PNB (when reported) or reported in the context of the PNB (when association with a PNB was not mentioned). Both prospective and retrospective studies which provided incidence of PBND at timepoints of interest (>48 hours to <2 weeks; >2 weeks to 6 weeks, 7 weeks to 5 months, 6 months to 1 year and >1 year durations) were included for review. Incidence data were used to provide pooled estimates (with 95% CI) of PBND at these time periods. Similar estimates were obtained to know the incidence of PBND with or without the use of US guidance. Additionally, PBND associated with individual PNB were obtained in a similar fashion with upper and lower limb PNB classified based on the anatomical location of needle insertion.FindingsThe overall incidence of PBND decreased with time, with the incidence being approximately 1% at <2 weeks’ time (Incidence per thousand (95% CI)= 9 (8; to 11)) to approximately 3/10 000 at 1 year (Incidence per thousand (95% CI)= 0. 3 (0.1; to 0.5)). Incidence of PBND differed for individual PNB with the highest incidence noted for interscalene block.ConclusionsOur review adds information to existing literature that the neurological complications are rarer but seem to display a higher incidence for some blocks more than others. Use of US guidance may be associated with a lower incidence of PBND especially in those PNBs reporting a higher pooled estimates. Future studies need to standardize the reporting of PBND at various timepoints and its association to PNB.
Details
- Title: Subtitle
- Neurological injury following peripheral nerve blocks: a narrative review of estimates of risks and the influence of ultrasound guidance
- Creators
- Ethan LemkeDavid Johnston - Belfast Health and Social Care TrustMatthew BehrensMelinda Seering - University of IowaBrie McConnellTejinder Singh Swaran Singh - University of Iowa Health CareRakesh Sondekoppam - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Regional Anesthesia and Pain Medicine, Vol.49(2), pp.122-132
- Publisher
- BMJ Publishing Group LTD; Secaucus
- DOI
- 10.1136/rapm-2023-104855
- PMID
- 37940348
- ISSN
- 1098-7339
- eISSN
- 1532-8651
- Language
- English
- Electronic publication date
- 11/01/2023
- Date published
- 02/2024
- Academic Unit
- Anesthesia
- Record Identifier
- 9984506258702771
Metrics
13 Record Views