Journal article
Neuropsychological Performance, Brain Imaging, and Driving Violations in Multiple Sclerosis
Archives of physical medicine and rehabilitation, Vol.95(10), pp.1818-1823
10/2014
DOI: 10.1016/j.apmr.2014.05.022
PMID: 24929025
Abstract
To examine the relationship between third ventricular width, a measure of thalamic brain atrophy, and motor vehicle violation type and frequency in a cohort of patients with multiple sclerosis (MS).
Retrospective cohort study.
Tertiary care university hospital.
Thirty-five individuals with clinically confirmed relapsing-remitting multiple sclerosis and 35 age-, sex-, and education-matched community-dwelling healthy comparisons (N=70). Participants were aged between 25 and 65 years.
Not applicable.
Data on motor vehicle violations were obtained from an online database (Iowa Courts Online). The violations were categorized as follows: (1) speeding, (2) nonmoving safety, (3) administrative, (4) alcohol-related offense, (5) moving safety, and (6) total violations. Neuropsychological performance in all major cognitive domains was obtained. Thalamic atrophy for the patients with MS was determined via third ventricular width measurement.
The MS group had a greater number of overall violations, administrative violations, and nonmoving safety violations. The groups differed on neuropsychological tasks measuring visuospatial skills, speeded language, learning, and executive functioning, after controlling for affective symptoms. Third ventricular width was associated with total violations as well as moving safety violations. Finally, third ventricular width accounted for a significant variance in driving violation frequency above and beyond demographic variables and neuropsychological factors.
There is an increased frequency of motor vehicle violations among patients with multiple sclerosis, and the number of violations can be predicted by thalamic brain atrophy.
Details
- Title: Subtitle
- Neuropsychological Performance, Brain Imaging, and Driving Violations in Multiple Sclerosis
- Creators
- Meaghan Dehning - Division of Cognitive Neuroscience, Department of Neurology, University of Iowa Carver College of Medicine, Iowa City, IowaJinsuh Kim - Department of Radiology, University of Iowa Carver College of Medicine, Iowa City, IowaChristopher M Nguyen - Division of Cognitive Neuroscience, Department of Neurology, University of Iowa Carver College of Medicine, Iowa City, IowaEzzatollah Shivapour - Division of Cognitive Neuroscience, Department of Neurology, University of Iowa Carver College of Medicine, Iowa City, IowaNatalie L Denburg - Division of Cognitive Neuroscience, Department of Neurology, University of Iowa Carver College of Medicine, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Archives of physical medicine and rehabilitation, Vol.95(10), pp.1818-1823
- DOI
- 10.1016/j.apmr.2014.05.022
- PMID
- 24929025
- NLM abbreviation
- Arch Phys Med Rehabil
- ISSN
- 0003-9993
- eISSN
- 1532-821X
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 10/2014
- Academic Unit
- Neurology; Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984020747602771
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