Journal article
Neuropsychological and psychiatric functioning pre- and posthematopoietic stem cell transplantation in adult cancer patients: A preliminary study
Journal of the International Neuropsychological Society, Vol.13(1), pp.172-177
01/2007
DOI: 10.1017/S1355617707070208
PMID: 17166316
Abstract
The current study characterizes cognitive and psychiatric status in
hematopoietic stem cell transplantation (HSCT) patients shortly before and
after transplant. Thirty adult patients were assessed prospectively
1–2 weeks before transplantation and 100 days posttransplantation on
neuropsychological and psychiatric measures. Before transplant,
participants showed mild impairments on several neuropsychological
measures, with the poorest performances occurring on learning and
attention. Psychiatric functioning was significantly elevated compared
with normative data. Significant improvements, however, were observed on
neuropsychological measures by 100 days after transplant. Depression and
anxiety scores also improved. Candidates for HSCT experienced mild diffuse
cognitive dysfunction and psychiatric morbidity before the procedure, but
these symptoms significantly improved by 3 months following their
transplant in this small sample. Education about these possible
pretransplant sequelae and the potential for rebound may be helpful to
patients and families as they prepare for this treatment and the recovery
period (JINS, 2007, 13, 172–177.)
Details
- Title: Subtitle
- Neuropsychological and psychiatric functioning pre- and posthematopoietic stem cell transplantation in adult cancer patients: A preliminary study
- Creators
- LEIGH J BEGLINGER - Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IowaKEVIN DUFF - Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IowaSARA VAN DER HEIDEN - Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IowaDAVID J MOSER - Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IowaJOHN D BAYLESS - Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IowaJANE S PAULSEN - Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IowaROGER GINGRICH - Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of the International Neuropsychological Society, Vol.13(1), pp.172-177
- Publisher
- Cambridge University Press; New York, USA
- DOI
- 10.1017/S1355617707070208
- PMID
- 17166316
- ISSN
- 1355-6177
- eISSN
- 1469-7661
- Number of pages
- 6
- Language
- English
- Date published
- 01/2007
- Academic Unit
- Psychiatry; Psychological and Brain Sciences; Medicine Administration; Internal Medicine
- Record Identifier
- 9984003919002771
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