Journal article
Neuropsychological function in obsessive-compulsive disorder
Comprehensive psychiatry, Vol.53(2), pp.167-175
2012
DOI: 10.1016/j.comppsych.2011.03.007
PMID: 21550029
Abstract
Obsessive-compulsive disorder (OCD) is a chronic disease characterized by repetitive, unwanted intrusive thoughts and ritualistic behaviors. Studies of neuropsychological functions in OCD have documented deficits in several cognitive domains, particularly with regard to visuospatial abilities, executive functioning, and motor speed. The objective of the present study was to investigate systematically the cognitive functioning of OCD patients who were free of medication and comorbid psychiatric disorders. In the present study, 72 OCD patients were compared with 54 healthy controls on their performance in a comprehensive neuropsychological battery. The Yale-Brown Obsessive Compulsive Scale and the Hamilton Depression Rating Scale were administered to the patients, and a semistructured interview form was used to evaluate the demographic features of the patients and control subjects. Overall, widespread statistically significant differences were found in tests related to verbal memory, global attention and psychomotor speed, and visuospatial and executive functions indicating a poorer performance of the OCD group. A closer scrutiny of these results suggests that the OCD group has difficulty in using an effective learning strategy that might be partly explained by their insufficient mental flexibility and somewhat poor planning abilities.
Details
- Title: Subtitle
- Neuropsychological function in obsessive-compulsive disorder
- Creators
- Raşit Tükel - Department of Psychiatry, Istanbul Faculty of Medicine, Istanbul University, Capa, Istanbul, TurkeyHakan Gürvit - Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul, TurkeyBanu Aslantaş Ertekin - Department of Psychiatry, Istanbul Faculty of Medicine, Istanbul University, Capa, Istanbul, TurkeySerap Oflaz - Department of Psychiatry, Istanbul Faculty of Medicine, Istanbul University, Capa, Istanbul, TurkeyErhan Ertekin - Department of Psychiatry, Istanbul Faculty of Medicine, Istanbul University, Capa, Istanbul, TurkeyBengi Baran - Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul, TurkeyŞükriye Akça Kalem - Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul, TurkeyPınar Elif Kandemir - Department of Psychiatry, Istanbul Faculty of Medicine, Istanbul University, Capa, Istanbul, TurkeyFiliz Alyanak Özdemiroğlu - Department of Psychiatry, Istanbul Faculty of Medicine, Istanbul University, Capa, Istanbul, TurkeyFigen Atalay - Haydarpasa Numune Education and Research Hospital, Psychiatry Clinic, Istanbul, Turkey
- Resource Type
- Journal article
- Publication Details
- Comprehensive psychiatry, Vol.53(2), pp.167-175
- DOI
- 10.1016/j.comppsych.2011.03.007
- PMID
- 21550029
- NLM abbreviation
- Compr Psychiatry
- ISSN
- 0010-440X
- eISSN
- 1532-8384
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 2012
- Academic Unit
- Psychiatry; Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984065376002771
Metrics
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