Journal article
Neuropsychological impairment in Tardive dyskinesia
Neuropsychology, Vol.8(2), pp.227-241
04/01/1994
DOI: 10.1037/0894-4105.8.2.227
Abstract
Tardive dyskinesia (TD) is a movement disorder secondary to neuroleptic treatment. Whether TD is associated with neurocognitive dysfunction is a controversial issue. We reviewed 31 published studies evaluating neuropsychological (NP) test results in schizophrenic patients with and without TD and found that TD was generally reported to be associated with cognitive impairment. Numerous methodological limitations, however, restrict the conclusions made about the relationship between cognition and dyskinesia. We therefore undertook a study in which 143 schizophrenic patients were evaluated on a comprehensive NP test battery. On both global and learning deficit scores, TD patients demonstrated greater impairment than did a matched comparison group. Two aspects of TD (severity and topography) were related to severity of cognitive impairment. These findings suggest that dyskinesia and cognition may share some underlying mechanism in schizophrenia. (PsycINFO Database Record (c) 2016 APA, all rights reserved)
Details
- Title: Subtitle
- Neuropsychological impairment in Tardive dyskinesia
- Creators
- Jane S PaulsenRobert K HeatonDilip V Jeste
- Resource Type
- Journal article
- Publication Details
- Neuropsychology, Vol.8(2), pp.227-241
- Publisher
- American Psychological Association
- DOI
- 10.1037/0894-4105.8.2.227
- ISSN
- 0894-4105
- eISSN
- 1931-1559
- Language
- English
- Date published
- 04/01/1994
- Academic Unit
- Psychiatry; Psychological and Brain Sciences
- Record Identifier
- 9984383317202771
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