Journal article
Neurosarcoidosis: Pathophysiology, Diagnosis, and Treatment
Neurology : neuroimmunology & neuroinflammation, Vol.8(6), p.e1084
11/2021
DOI: 10.1212/NXI.0000000000001084
PMCID: PMC8495503
PMID: 34607912
Abstract
Although often regarded as a protean illness with myriad clinical and imaging manifestations, neurosarcoidosis typically presents as recognizable syndromes that can be approached in a rational, systematic fashion. Understanding of neurosarcoidosis has progressed significantly in recent years, including updated diagnostic criteria and advances in treatment. The diagnosis of neurosarcoidosis is established by the clinical syndrome, imaging and histopathological findings, and exclusion of other causes. Mounting evidence supports the use of tumor necrosis factor inhibitors as an important addition to the therapeutic armamentarium, along with glucocorticoids and steroid-sparing cytotoxic immunosuppressants. In this narrative review, we summarize recent advances in the diagnosis and treatment of neurosarcoidosis.
Details
- Title: Subtitle
- Neurosarcoidosis: Pathophysiology, Diagnosis, and Treatment
- Creators
- Michael J BradshawSiddharama PawateLaura L KothTracey A Cho - University of Iowa, NeurologyJeffrey M Gelfand
- Resource Type
- Journal article
- Publication Details
- Neurology : neuroimmunology & neuroinflammation, Vol.8(6), p.e1084
- DOI
- 10.1212/NXI.0000000000001084
- PMID
- 34607912
- PMCID
- PMC8495503
- NLM abbreviation
- Neurol Neuroimmunol Neuroinflamm
- ISSN
- 2332-7812
- eISSN
- 2332-7812
- Language
- English
- Date published
- 11/2021
- Academic Unit
- Neurology; Iowa Neuroscience Institute
- Record Identifier
- 9984187040902771
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