Journal article
Neurotrophins and hearing dysfunction: Comparing models to stop nerve fiber loss
Drug discovery today. Disease models, Vol.3(4), pp.391-396
2006
DOI: 10.1016/j.ddmod.2006.10.011
Abstract
Two neurotrophins and their high affinity tyrosine kinase receptors mediate neuronal survival and fiber guidance in the developing ear. Neurotrophins are also essential for adult sensory survival. New models based on other tyrosine kinase receptor treatments may help maintain inner ear innervation beyond the apparently inevitable loss of hair cells with age, one major source of neurotrophins in the adult ear, and may improve prospects to treat hearing loss.
Kathryn Albers – University of Pittsburgh, Pittsburgh, USA
Details
- Title: Subtitle
- Neurotrophins and hearing dysfunction: Comparing models to stop nerve fiber loss
- Creators
- Theodore F WissinkChad MoesKirk W BeiselBernd Fritzsch
- Resource Type
- Journal article
- Publication Details
- Drug discovery today. Disease models, Vol.3(4), pp.391-396
- DOI
- 10.1016/j.ddmod.2006.10.011
- ISSN
- 1740-6757
- eISSN
- 1740-6757
- Publisher
- Elsevier Ltd
- Language
- English
- Date published
- 2006
- Academic Unit
- Iowa Neuroscience Institute; Biology; Craniofacial Anomalies Research Center
- Record Identifier
- 9984070564802771
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