Journal article
New Complex Recombinant Genotype of Hepatitis B Virus Identified in Vietnam
Journal of virology, Vol.82(11), pp.5657-5663
06/2008
DOI: 10.1128/JVI.02556-07
PMCID: PMC2395174
PMID: 18353958
Abstract
A novel variant of hepatitis B virus was identified in Vietnam. This strain (HBV-VH24) had a novel intergenotypic recombination between genotypes A, C, and G. VH24 showed high similarity (98.3 to 98.9%) to the “aberrant strains” among Vietnamese isolates reported by Hannoun et al. (C. Hannoun et al., J. Gen. Virol. 81:2267-2272, 2000) and also had similar breakpoints of recombination. Phylogenetic analysis of the complete genome of these strains formed a separate clade. Furthermore, their pre-S/S gene-encoded seven unique conserved amino acid residues were not present in other genotypes. These findings support the designation of the new genotype I.
Details
- Title: Subtitle
- New Complex Recombinant Genotype of Hepatitis B Virus Identified in Vietnam
- Creators
- Tran Thien Tuan Huy - Department of Pathology, National Institute of Infectious Diseases, Tokyo, JapanTrinh Thi Ngoc - Department of Pathology, National Institute of Infectious Diseases, Tokyo, JapanKenji Abe - Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan
- Resource Type
- Journal article
- Publication Details
- Journal of virology, Vol.82(11), pp.5657-5663
- DOI
- 10.1128/JVI.02556-07
- PMID
- 18353958
- PMCID
- PMC2395174
- NLM abbreviation
- J Virol
- ISSN
- 0022-538X
- eISSN
- 1098-5514
- Publisher
- American Society for Microbiology (ASM)
- Language
- English
- Date published
- 06/2008
- Academic Unit
- Gastroenterology and Hepatology; Internal Medicine
- Record Identifier
- 9984094380102771
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