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New Diketopiperazine Metabolites from the Sclerotia of Aspergillus ochraceus
Journal article   Peer reviewed

New Diketopiperazine Metabolites from the Sclerotia of Aspergillus ochraceus

Florecita S de Guzman, James B Gloer, Donald T Wicklow and Partick F Dowd
Journal of natural products (Washington, D.C.), Vol.55(7), pp.931-939
07/01/1992
DOI: 10.1021/np50085a013
PMID: 1402958

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Abstract

Three new diketopiperazine-containing metabolites 1-3 have been isolated from the sclerotia of Aspergillus ochraceus (NRRL 3519) by chromatography on Sephadex LH-20 and reversed-phase hplc. The structures of these compounds were established using extensive high-field ID and 2D nmr experiments. All three compounds cause moderate reduction in weight gain in assays against the lepidopteran crop pest Helicoverpa zea. © 1992, American Chemical Society. All rights reserved.

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