Journal article
New antifungal metabolites from the coprophilous fungus Cercophorasordarioides
Canadian journal of chemistry, Vol.75(6), pp.768-772
06/01/1997
DOI: 10.1139/v97-093
Abstract
A chemical investigation of the coprophilous fungus Cercophorasordarioides has led to the isolation of arthrinone (1), a known fungal metabolite, and three new related compounds: 1-dehydroxyarthrinone (2), 3a,9a-deoxy-3a-hydroxy-1-dehydroxyarthrinone (3), and cerdarin (4). These metabolites were obtained from antifungal ethyl acetate extracts of liquid cultures of C. sordarioides through bioassay-guided fractionation, and their structures were assigned on the basis of 1D-NMR, HMQC, and HMBC results. Compounds 2 and 4 exhibited anti-Candida activity. Key words: antifungal, fungal metabolite, natural product, Cercophorasordarioides.
Details
- Title: Subtitle
- New antifungal metabolites from the coprophilous fungus Cercophorasordarioides
- Creators
- Authrine C WhyteKatherine B GloerJames B GloerBrenda KosterDavid Malloch
- Resource Type
- Journal article
- Publication Details
- Canadian journal of chemistry, Vol.75(6), pp.768-772
- DOI
- 10.1139/v97-093
- ISSN
- 0008-4042
- eISSN
- 1480-3291
- Language
- English
- Date published
- 06/01/1997
- Academic Unit
- Chemistry
- Record Identifier
- 9984216582802771
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