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New form of familial Parkinson-dementia syndrome: clinical and pathologic findings
Journal article   Peer reviewed

New form of familial Parkinson-dementia syndrome: clinical and pathologic findings

Marina Mata, K Dorovini-Zis, M Wilson and A B Young
Neurology, Vol.33(11), pp.1439-1443
11/1983
DOI: 10.1212/WNL.33.11.1439
PMID: 6685236

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Abstract

We studied a family in which three siblings had a syndrome characterized by parkinsonism features, mental deterioration, pyramidal signs, and abnormal eye movements beginning in the third decade. The pathology resembled that of progressive supranuclear palsy or the Parkinson-dementia complex of Guam, but these were excluded by the clinical presentation. This syndrome appears to be a new entity.
Parkinson Disease - pathology Dementia - pathology Humans Brain - pathology Adult Female Male Parkinson Disease - genetics Dementia - genetics Syndrome

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