Journal article
New insights into Entamoeba histolytica pathogenesis
Current opinion in infectious diseases, Vol.21(5), pp.489-494
10/2008
DOI: 10.1097/QCO.0b013e32830ce75f
PMID: 18725798
Abstract
Purpose of review
Entamoeba histolytica is an important global pathogen and a leading cause of parasitic death worldwide. This article summarizes significant research findings over the last year.
Recent findings
Efforts have focused primarily on identification of novel virulence determinants in E histolytica, transcriptional profiling during tissue invasion and stage conversion, and characterization of basic cell biological processes. Additionally, new techniques for gene silencing have been identified.
Summary
A comprehensive examination of the parasite lifestyle on a whole genome level has been undertaken, allowing identification of new virulence genes and signaling pathways and processes relevant to amebic biology.
Details
- Title: Subtitle
- New insights into Entamoeba histolytica pathogenesis
- Creators
- Leigh A. Baxt - Stanford UniversityUpinder Singh - Stanford University
- Resource Type
- Journal article
- Publication Details
- Current opinion in infectious diseases, Vol.21(5), pp.489-494
- DOI
- 10.1097/QCO.0b013e32830ce75f
- PMID
- 18725798
- NLM abbreviation
- Curr Opin Infect Dis
- ISSN
- 0951-7375
- eISSN
- 1473-6527
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 6
- Grant note
- R01AI053724 / NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID) T32 AI007328; R01 AI053724-05; R01 AI053724 / NIAID NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID)
- Language
- English
- Date published
- 10/2008
- Academic Unit
- Internal Medicine
- Record Identifier
- 9985244545402771
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