Journal article
New p-Terphenyl and Polyketide Metabolites from the Sclerotia of Penicillium raistrickii
Journal of natural products (Washington, D.C.), Vol.61(9), pp.1115-1119
09/25/1998
DOI: 10.1021/np980188o
PMID: 9748377
Abstract
Three new p-terphenyls (1-3), a new xanthone derivative (4), and two known fungal metabolites (5 and 6) have been isolated from the sclerotia of Penicillium raistrickii (NRRL 2039). The structures for 3,3''-dihydroxy-6'- desmethylterphenyllin (1); 3'-demethoxy-6'-desmethyl-5'-methoxycandidusin B (2); 6'-desmethylcandidusin B (3); and 1,3,5,6-tetrahydroxy-8-methylxanthone (4) were determined on the basis of HRMS and NMR data. Although compounds 1 and 4 exhibited mild antiinsectan and antibacterial activity, griseofulvin (5) was responsible for most of the activity of the sclerotial extract in dietary assays against the corn earworm Helicoverpa zea.
Details
- Title: Subtitle
- New p-Terphenyl and Polyketide Metabolites from the Sclerotia of Penicillium raistrickii
- Creators
- Gilbert N Belofsky - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, and Agricultural Research Service, National Center forAgricultural Utilization Research, USDA, Peoria, Illinois 61604Katherine B Gloer - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, and Agricultural Research Service, National Center forAgricultural Utilization Research, USDA, Peoria, Illinois 61604James B Gloer - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, and Agricultural Research Service, National Center forAgricultural Utilization Research, USDA, Peoria, Illinois 61604Donald T Wicklow - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, and Agricultural Research Service, National Center forAgricultural Utilization Research, USDA, Peoria, Illinois 61604Patrick F Dowd - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, and Agricultural Research Service, National Center forAgricultural Utilization Research, USDA, Peoria, Illinois 61604
- Resource Type
- Journal article
- Publication Details
- Journal of natural products (Washington, D.C.), Vol.61(9), pp.1115-1119
- Publisher
- American Chemical Society
- DOI
- 10.1021/np980188o
- PMID
- 9748377
- ISSN
- 0163-3864
- eISSN
- 1520-6025
- Language
- English
- Date published
- 09/25/1998
- Academic Unit
- Center for Social Science Innovation; Chemistry
- Record Identifier
- 9984216713502771
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