New strategies for prevention of ischemic stroke: the LIFE study

Harold P Adams

doi:10.1007/s11910-003-0036-7

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New strategies for prevention of ischemic stroke: the LIFE study

Journal article

Peer reviewed

New strategies for prevention of ischemic stroke: the LIFE study

Harold P Adams

Current neurology and neuroscience reports, Vol.3(1), pp.46-51

01/2003

DOI: 10.1007/s11910-003-0036-7

PMID: 12507410

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Abstract

New strategies to lower the risk of stroke among high-risk persons are being developed. Therapies such as cholesterol-lowering medications and newer antihypertensive agents appear to complement traditional antithrombotic drugs and surgical procedures. Of particular interest is the use of the newer angiotensin-converting enzyme (ACE) inhibitors, which appear to have an effect on stabilizing the vascular endothelium. The Losartan Intervention For Endpoint (LIFE) reduction in hypertension study provides additional data to support the use of the ACE inhibitors to lower the risk of stroke among patients with hypertension and vascular diseases.

Stroke - prevention & control

Humans

Middle Aged

Risk Factors

Hypertension - drug therapy

Treatment Outcome

Antihypertensive Agents - therapeutic use

Hypertension - physiopathology

Randomized Controlled Trials as Topic

Stroke - etiology

Atenolol - therapeutic use

Angiotensin-Converting Enzyme Inhibitors - therapeutic use

Hypertrophy, Left Ventricular - complications

Losartan - therapeutic use

Aged, 80 and over

Hypertension - complications

Stroke - epidemiology

Aged

Blood Pressure - drug effects

Hypertrophy, Left Ventricular - drug therapy

Hypertrophy, Left Ventricular - physiopathology

Details

Title: Subtitle: New strategies for prevention of ischemic stroke: the LIFE study
Creators: Harold P Adams - Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52246, USA. harold-adams@uiowa.edu
Resource Type: Journal article
Publication Details: Current neurology and neuroscience reports, Vol.3(1), pp.46-51
Publisher: United States
DOI: 10.1007/s11910-003-0036-7
PMID: 12507410
ISSN: 1528-4042
eISSN: 1534-6293
Language: English
Date published: 01/2003
Academic Unit: Neurology; Iowa Neuroscience Institute
Record Identifier: 9984020625102771

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