New variant of varicella-zoster virus

Graham A Tipples; Gwen M Stephens; Chris Sherlock; Margrit Bowler; Benny Hoy; Darrel Cook; Charles Grose

doi:10.3201/eid0812.020118

Back

Journal article

Open access

Peer reviewed

New variant of varicella-zoster virus

Graham A Tipples, Gwen M Stephens, Chris Sherlock, Margrit Bowler, Benny Hoy, Darrel Cook and Charles Grose

Emerging infectious diseases, Vol.8(12), pp.1504-1505

12/2002

DOI: 10.3201/eid0812.020118

PMCID: PMC2738511

PMID: 12498673

Files and links (1)

url

https://doi.org/10.3201/eid0812.020118View

Published (Version of record) Open Access

Abstract

In 1998, a varicella-zoster virus glycoprotein E (gE) mutant virus (VZV-MSP) was isolated from a child with chickenpox. VZV-MSP, representing a second VZV serotype, was considered a rarity. We isolated another VZV-MSP-like virus from an elderly man with herpes zoster. These gE mutant viruses may have arisen through independent mutation or may represent a distinct VZV subpopulation that emerged more than 50 years ago.

Genome, Viral

Antiviral Agents - therapeutic use

Herpesvirus 3, Human - classification

Humans

2-Aminopurine - therapeutic use

Male

Herpesvirus 3, Human - genetics

Herpes Zoster - drug therapy

2-Aminopurine - analogs & derivatives

Polymerase Chain Reaction

Herpes Zoster - physiopathology

Herpesvirus 3, Human - pathogenicity

Aged

Child

Serotyping

Details

Title: Subtitle: New variant of varicella-zoster virus
Creators: Graham A Tipples - National Microbiology Laboratory, Winnipeg, Manitoba, Canada. graham_tipples@hc-sc.gc.ca
Gwen M Stephens
Chris Sherlock
Margrit Bowler
Benny Hoy
Darrel Cook
Charles Grose
Resource Type: Journal article
Publication Details: Emerging infectious diseases, Vol.8(12), pp.1504-1505
DOI: 10.3201/eid0812.020118
PMID: 12498673
PMCID: PMC2738511
NLM abbreviation: Emerg Infect Dis
ISSN: 1080-6040
eISSN: 1080-6059
Language: English
Date published: 12/2002
Academic Unit: Stead Family Department of Pediatrics; Infectious Disease (Pediatrics)
Record Identifier: 9984093506302771

Metrics

17 Record Views

23 Times Cited - Web of Science