Newborn society of fetal urology grade 3 hydronephrosis is equivalent to preserved percentage differential function

Bradley A Erickson; Max Maizels; Richard M Shore; Joseph F Pazona; Jennifer A Hagerty; Elizabeth B Yerkes; Antonio H Chaviano; William E Kaplan; Earl Y Cheng

doi:10.1016/j.jpurol.2007.01.196

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Newborn society of fetal urology grade 3 hydronephrosis is equivalent to preserved percentage differential function

Journal article

Peer reviewed

Newborn society of fetal urology grade 3 hydronephrosis is equivalent to preserved percentage differential function

Bradley A Erickson, Max Maizels, Richard M Shore, Joseph F Pazona, Jennifer A Hagerty, Elizabeth B Yerkes, Antonio H Chaviano, William E Kaplan and Earl Y Cheng

Journal of pediatric urology, Vol.3(5), pp.382-386

2007

DOI: 10.1016/j.jpurol.2007.01.196

PMID: 18947778

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Abstract

In newborn hydronephrosis (HN), the level of differential function (%df) measured by diuretic renography (DR) is used to judge the need for pyeloplasty. As DR testing is complex, we sought to determine if grading the level of HN (Society of Fetal Urology grade, SFU Gr) by a simple ultrasound correlates with percentage differential function (%df) and thereby obviates the need to perform DR. Between 1990 and 2003 our institution prospectively enrolled all cases of fetal HN who showed unilateral newborn SFU Gr HN ≥3. The cases underwent standardized testing. DR was done using the method of Well-Tempered Renography which was then followed by ultrasound (US). The US studies were performed while the hydration induced by DR was in effect. The level of %df was categorized as preserved (≥40%) or reduced (<40%). Cases were excluded if there was an additional urological abnormality (e.g. ureterocele). There were 71 cases that met our study criteria. The SFU Gr HN was 3 ( n = 33) or 4 ( n = 38). Kidneys with SFU Gr 3 HN showed preserved %df (33/33,100%) (mean = 50.1 ± 3.6) significantly more often than kidneys with SFU Gr 4 HN (27/38, 71%) (mean = 42.2 ± 13.9) (RR = 1.41, 95% CI (1.15–1.72), p < 0.001). In newborns with a history of fetal HN, the postnatal finding of SFU Gr 3 HN uniformly correlates with preserved %df. Standardized hydration prior to US study is done to assure consistency in measurement of the SFU Gr HN. Determining the duration of the relationship between SFU Gr 3 HN and preserved %df will require prospective, longitudinal studies.

Diuretic renal scan

Infant

Ultrasound

Hydronephrosis

Details

Title: Subtitle: Newborn society of fetal urology grade 3 hydronephrosis is equivalent to preserved percentage differential function
Creators: Bradley A Erickson - Division of Urology, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614, USA
Max Maizels - Division of Urology, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614, USA
Richard M Shore - Department of Radiology, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL, USA
Joseph F Pazona - Division of Urology, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614, USA
Jennifer A Hagerty - Division of Urology, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614, USA
Elizabeth B Yerkes - Division of Urology, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614, USA
Antonio H Chaviano - Division of Urology, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614, USA
William E Kaplan - Division of Urology, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614, USA
Earl Y Cheng - Division of Urology, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614, USA
Resource Type: Journal article
Publication Details: Journal of pediatric urology, Vol.3(5), pp.382-386
Publisher: Elsevier Ltd
DOI: 10.1016/j.jpurol.2007.01.196
PMID: 18947778
ISSN: 1477-5131
eISSN: 1873-4898
Language: English
Date published: 2007
Academic Unit: Urology
Record Identifier: 9984051999502771

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