Journal article
Nicardipine after spinal cord compression in the lamb
Surgical neurology, Vol.31(2), pp.101-110
1989
DOI: 10.1016/0090-3019(89)90319-4
PMID: 2922646
Abstract
To study the effects of the calcium channel blocker nicardipine on spinal cord blood flow and spinal evoked potentials, the following study was undertaken. After cord compression, which was productive of paraparesis, nicardipine was administered intravenously in 10 anesthetized lambs. Ten control animals were subjected to compression but received saline instead. Nicardipine produced a significant decrease in mean arterial pressure when compared to the control group. Thirty minutes after compression, spinal cord blood flow also was lower in the nicardipine group compared with controls. Spinal evoked potentials did not recover after compression in either group.
Details
- Title: Subtitle
- Nicardipine after spinal cord compression in the lamb
- Creators
- Patrick W HitchonTodd HansenThomas McKayRichard A GirtonGregg N DysteMartin D Sokoll
- Resource Type
- Journal article
- Publication Details
- Surgical neurology, Vol.31(2), pp.101-110
- DOI
- 10.1016/0090-3019(89)90319-4
- PMID
- 2922646
- NLM abbreviation
- Surg Neurol
- ISSN
- 0090-3019
- eISSN
- 1879-3339
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1989
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Anesthesia; Urology; Neurosurgery
- Record Identifier
- 9984040348702771
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