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No Evidence for Genetic-Linkage of Gilles-De-La-Tourette Syndrome on Chromosome-7 and Chromosome-18
Journal article   Open access   Peer reviewed

No Evidence for Genetic-Linkage of Gilles-De-La-Tourette Syndrome on Chromosome-7 and Chromosome-18

P. Heutink, B J M van de Wetering, G. J. Breedveld, J Weber, L. A. Sandkuyl, E J Devor, A. Heiberg, M. F. Niermeijer and B. A. Oostra
Journal of medical genetics, Vol.27(7), pp.433-436
07/01/1990
DOI: 10.1136/jmg.27.7.433
PMID: 02395161
url
https://doi.org/10.1136/jmg.27.7.433View
Published (Version of record) Open Access

Abstract

Gilles de la Tourette syndrome is a heritable neuropsychiatric disorder. In order to determine the chromosomal localisation of the locus involved, genetic linkage studies were initiated in six extended families. The Gilles de la Tourette gene has been tentatively assigned to chromosome 18q22.1. In our present study no evidence for genetic linkage on chromosome 18 and chromosome 7 was obtained. Data from the markers tested made it possible to exclude the whole of chromosome 18 and the chromosome 7q21.3-qter region as a site for the Gilles de la Tourette gene.
Obstetrics and Gynecology

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