Journal article
Nodular secondary syphilis with associated granulomatous inflammation: case report and literature review
Journal of cutaneous pathology, Vol.41(4), pp.370-379
04/2014
DOI: 10.1111/cup.12293
PMID: 24447075
Abstract
A 62-year-old male presented with a 10-day history of a diffuse, erythematous papular rash sparing the palms and soles. Histopathologic examination of a skin lesion showed loose non-caseating granulomas in a lymphoplasmacytic background. Scattered spirochetes were identified by Treponema pallidum immunohistochemistry, in keeping with a diagnosis of secondary syphilis. Granulomatous inflammation in secondary syphilis is uncommon. A review of the literature reveals that the majority of prior reported cases of granulomatous secondary syphilis share similar characteristics to this case; namely, a papular or nodular clinical presentation, sparing of the palms and soles, and collections of epithelioid histiocytes with associated lymphocytes and variable numbers of plasma cells.
Details
- Title: Subtitle
- Nodular secondary syphilis with associated granulomatous inflammation: case report and literature review
- Creators
- Carolyn Rysgaard - Department of Pathology, University of Iowa, Iowa City, IA, USAErik AlexanderBrian L Swick
- Resource Type
- Journal article
- Publication Details
- Journal of cutaneous pathology, Vol.41(4), pp.370-379
- Publisher
- United States
- DOI
- 10.1111/cup.12293
- PMID
- 24447075
- ISSN
- 0303-6987
- eISSN
- 1600-0560
- Language
- English
- Date published
- 04/2014
- Academic Unit
- Dermatology; Pathology
- Record Identifier
- 9984025355302771
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