Journal article
Non-Hodgkin Lymphomas of Mice
Blood cells, molecules, & diseases, Vol.27(1), pp.217-222
01/2001
DOI: 10.1006/bcmd.2000.0375
PMID: 11358382
Abstract
ABSTRACT
Studies of lymphoid neoplasms occurring in normal or genetically engineered mice have revealed parallels and differences to non-Hodgkin lymphomas (NHL) of humans. Some mouse lymphomas have strong histologic similarities to the human NHL subsets including precursor B- and T-cell lymphoblastic, small lymphocytic, splenic marginal zone, and diffuse large-cell B-cell lymphomas (DLCL); whether molecular parallels also exist is under study. Others mouse types such as sIg+ lymphoblastic B-cell lymphoma have no histologic equivalent in human NHL even though they share molecular deregulation of BCL6 with human DLCL. Finally, Burkitt lymphoma does not appear to occur naturally in mice, but it can be induced with appropriately engineered transgenes.
Details
- Title: Subtitle
- Non-Hodgkin Lymphomas of Mice
- Creators
- Mitsuo Hori - Laboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20892Shao Xiang - Laboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20892Chen-Feng Qi - Laboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20892Sisir K Chattopadhyay - Laboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20892Torgny N Fredrickson - Laboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20892Janet W Hartley - Laboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20892Alexander L Kovalchuk - Laboratory of Genetics, Office of Laboratory Animal Science, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20892Georg W Bornkamm - GSF Forschungszentrum für Umwelt und Gesundheit, Institut für Klinische Molekularbiologie und Tumorgenetik, Munich, GermanySiegfried Janz - Laboratory of Genetics, Office of Laboratory Animal Science, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20892Neal G Copeland - Mouse Cancer Genetics Program, Office of Laboratory Animal Science, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20892Nancy A Jenkins - Mouse Cancer Genetics Program, Office of Laboratory Animal Science, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20892Jerrold M Ward - Veterinary and Tumor Pathology Section, Office of Laboratory Animal Science, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20892Herbert C Morse - Laboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, 20892
- Resource Type
- Journal article
- Publication Details
- Blood cells, molecules, & diseases, Vol.27(1), pp.217-222
- Publisher
- Elsevier Inc
- DOI
- 10.1006/bcmd.2000.0375
- PMID
- 11358382
- ISSN
- 1079-9796
- eISSN
- 1096-0961
- Language
- English
- Date published
- 01/2001
- Academic Unit
- Pathology
- Record Identifier
- 9984083897102771
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