Journal article
Non-exercise estimated cardiorespiratory fitness: Associations with brain structure, cognition, and memory complaints in older adults
Mental health and physical activity, Vol.4(1), pp.5-11
2011
DOI: 10.1016/j.mhpa.2011.01.001
PMCID: PMC3146052
PMID: 21808657
Abstract
There is increasing evidence that cardiorespiratory fitness (CRF) is associated with brain structure and function, and improvements in CRF through exercise training have been associated with neural and cognitive functioning in older adults. The objectives of this study were to validate the use of a non-exercise estimate of CRF, and to examine its association with cognitive function, brain structure and subjective memory complaints. Low active, older adults (\nN = 86;\nMage = 65.14) completed a physician-supervised maximal exercise test, a 1-mile timed walk, several measures of cognitive function, and a 3 T structural MRI. Fitness was also calculated from an equation derived by\nJurca et al. (2005) based on age, sex, body mass index, resting heart rate, and self-reported physical activity level. Analyses indicated that all three measures of CRF were significantly correlated with one another. In addition, measures of cognitive function, hippocampus volume, and memory complaints were significantly correlated with each measure of fitness. These findings have implications for using a low-risk, low-cost, non-exercise estimate of CRF in determining fitness associations with brain structure and cognitive function in older adults. As such, this measure may have utility for larger population based studies. Further validation is required, as is determination of whether such relationships hold over the course of exercise interventions.\n► A non-exercise estimate of CRF is significantly correlated with maximal and sub-maximal estimates of CRF. ► No differences were found between strength of association of each fitness measure with processing speed, spatial working memory, and hippocampal volume. ► Each cardiorespiratory measure accounts for significant variance in hippocampal volume when controlling for age, education, physical activity, and BMI.
Details
- Title: Subtitle
- Non-exercise estimated cardiorespiratory fitness: Associations with brain structure, cognition, and memory complaints in older adults
- Creators
- Edward McAuley - University of Illinois, Urbana-Champaign, IL, United StatesAmanda N Szabo - University of Illinois, Urbana-Champaign, IL, United StatesEmily L Mailey - University of Illinois, Urbana-Champaign, IL, United StatesKirk I Erickson - University of Pittsburgh, Pittsburg, PA, United StatesMichelle Voss - University of Illinois, Urbana-Champaign, IL, United StatesSiobhan M White - University of Illinois, Urbana-Champaign, IL, United StatesThomas R Wójcicki - University of Illinois, Urbana-Champaign, IL, United StatesNeha Gothe - University of Illinois, Urbana-Champaign, IL, United StatesErin A Olson - University of Illinois, Urbana-Champaign, IL, United StatesSean P Mullen - University of Illinois, Urbana-Champaign, IL, United StatesArthur F Kramer - University of Illinois, Urbana-Champaign, IL, United States
- Resource Type
- Journal article
- Publication Details
- Mental health and physical activity, Vol.4(1), pp.5-11
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.mhpa.2011.01.001
- PMID
- 21808657
- PMCID
- PMC3146052
- ISSN
- 1755-2966
- eISSN
- 1878-0199
- Language
- English
- Date published
- 2011
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984070859902771
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