Journal article
Non-pharmacological management of a hemodynamically significant patent ductus arteriosus
Seminars in fetal & neonatal medicine, Vol.23(4), pp.245-249
08/2018
DOI: 10.1016/j.siny.2018.03.008
PMID: 29580939
Abstract
The association between the patent ductus arteriosus (PDA) and neonatal morbidity, mortality and poor neurodevelopmental outcome in later childhood has been the focus of intense debate for decades. The lack of evidence supporting therapeutic strategies aimed at achieving PDA closure has led to the widespread adoption of conservative management aimed at mitigating the impact of shunt volume without achieving ductal closure. In this article, we review this management approach, describe the supportive evidence and potential complications associated with this strategy.
Details
- Title: Subtitle
- Non-pharmacological management of a hemodynamically significant patent ductus arteriosus
- Creators
- A Smith - Department of Neonatology, The Rotunda Hospital, Dublin, IrelandP.J McNamara - Department of Paediatrics, University of Toronto, Toronto, Ontario, CanadaA.F EL-Khuffash - Department of Neonatology, The Rotunda Hospital, Dublin, Ireland
- Resource Type
- Journal article
- Publication Details
- Seminars in fetal & neonatal medicine, Vol.23(4), pp.245-249
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.siny.2018.03.008
- PMID
- 29580939
- ISSN
- 1744-165X
- eISSN
- 1878-0946
- Grant note
- name: The HIP Trial, award: EU FP7/2007–2013, 260777; name: Friends of the Rotunda Research, award: FoR/EQUIPMENT/101572; name: Health Research Board Mother and Baby Clinical Trials Network Ireland, award: CTN-2014-10; name: Medical Research Charities Group/Health Research Board/Friends of the Rotunda Research, award: MRCG-2013-9
- Language
- English
- Date published
- 08/2018
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology; Internal Medicine
- Record Identifier
- 9984093320802771
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