Journal article
Noninvasive Brain Stimulation in Pediatric Attention-Deficit Hyperactivity Disorder (ADHD): A Review
Journal of child neurology, Vol.31(6), pp.784-96
05/2016
DOI: 10.1177/0883073815615672
PMCID: PMC4833526
PMID: 26661481
Abstract
Attention-deficit hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental disorders in the pediatric population. The clinical management of ADHD is currently limited by a lack of reliable diagnostic biomarkers and inadequate therapy for a minority of patients who do not respond to standard pharmacotherapy. There is optimism that noninvasive brain stimulation may help to address these limitations. Transcranial magnetic stimulation and transcranial direct current stimulation are 2 methods of noninvasive brain stimulation that modulate cortical excitability and brain network activity. Transcranial magnetic stimulation can be used diagnostically to probe cortical neurophysiology, whereas daily use of repetitive transcranial magnetic stimulation or transcranial direct current stimulation can induce long-lasting and potentially therapeutic changes in targeted networks. In this review, we highlight research showing the potential diagnostic and therapeutic applications of transcranial magnetic stimulation and transcranial direct current stimulation in pediatric ADHD. We also discuss the safety and ethics of using these tools in the pediatric population.
Details
- Title: Subtitle
- Noninvasive Brain Stimulation in Pediatric Attention-Deficit Hyperactivity Disorder (ADHD): A Review
- Creators
- Belen Rubio - Child and Adolescent Psychiatry Department, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain Both are co-primary authorsAaron D Boes - Berenson-Allen Center for Noninvasive Brain Stimulation, Division of Cognitive Neurology, Department of Neurology, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, USA Harvard Medical School, Department of Pediatric Neurology, Massachusetts General Hospital, Boston, MA, USA Both are co-primary authors. rubiobelen@gmail.com aboes@partners.orgSimon Laganiere - Berenson-Allen Center for Noninvasive Brain Stimulation, Division of Cognitive Neurology, Department of Neurology, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, USAAlexander Rotenberg - Berenson-Allen Center for Noninvasive Brain Stimulation, Division of Cognitive Neurology, Department of Neurology, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, USA Pediatric Neuromodulation Program, Division of Epilepsy and Neurophysiology, Department of Neurology, Children's Hospital Boston, Harvard Medical School, Boston, MA, USADanique Jeurissen - Berenson-Allen Center for Noninvasive Brain Stimulation, Division of Cognitive Neurology, Department of Neurology, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, USA Department of Vision and Cognition, Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The NetherlandsAlvaro Pascual-Leone - Berenson-Allen Center for Noninvasive Brain Stimulation, Division of Cognitive Neurology, Department of Neurology, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, USA
- Resource Type
- Journal article
- Publication Details
- Journal of child neurology, Vol.31(6), pp.784-96
- DOI
- 10.1177/0883073815615672
- PMID
- 26661481
- PMCID
- PMC4833526
- NLM abbreviation
- J Child Neurol
- ISSN
- 0883-0738
- eISSN
- 1708-8283
- Publisher
- United States
- Grant note
- R01 NS088583 / NINDS NIH HHS R01HD069776 / NICHD NIH HHS R21 HD07616 / NICHD NIH HHS R25 NS065743 / NINDS NIH HHS R01NS073601 / NINDS NIH HHS UL1 RR025758 / NCRR NIH HHS R21 MH099196 / NIMH NIH HHS R25NS065743-05 / NINDS NIH HHS R21 NS085491 / NINDS NIH HHS R01 100186 / PHS HHS R21 NS082870 / NINDS NIH HHS
- Language
- English
- Date published
- 05/2016
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Neurology; Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Neurology (Pediatrics)
- Record Identifier
- 9984020615502771
Metrics
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