Nonlinear magnetic stereotaxis : three-dimensional, in vivo remote magnetic manipulation of a small object in canine brain

M. S GRADY; M. A HOWARD; J. A MOLLOY; R. C RITTER; E. G QUATE; G. T GILLIES

doi:10.1118/1.596520

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Nonlinear magnetic stereotaxis : three-dimensional, in vivo remote magnetic manipulation of a small object in canine brain

Journal article

Peer reviewed

Nonlinear magnetic stereotaxis : three-dimensional, in vivo remote magnetic manipulation of a small object in canine brain

M. S GRADY, M. A HOWARD, J. A MOLLOY, R. C RITTER, E. G QUATE and G. T GILLIES

Medical physics (Lancaster), Vol.17(3), pp.405-415

1990

DOI: 10.1118/1.596520

PMID: 2200950

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Abstract

In a series of in vivo experiments on five adult canines, a small cylindrical permanent magnet (∼5-mm diameter×5 mm long) was magnetically moved under fluoroscopic guidance from an occipital-lobe burr hole to a predetermined destination within the brain and then removed. On three of the animals, dorsal and temporal skull markers were used to establish a coordinate system against which the motions of the seed were referenced. These procedures were sufficiently accurate to permit the guided motion of the seed along nonlinear paths within the brain, including traversal of the midline through the corpus callosum. For removal, the seed could be steered either to a frontal lobe location for extraction through an auxiliary burr hole, or back to the same burr hole through which it had been inserted. This article discusses the way in which stereotactic motions were obtained, the performance limits of the instrumentation and the precision of motion achieved.

Biological and medical sciences

Investigative techniques, diagnostic techniques (general aspects)

Medical sciences

Details

Title: Subtitle: Nonlinear magnetic stereotaxis : three-dimensional, in vivo remote magnetic manipulation of a small object in canine brain
Creators: M. S GRADY - Univ. Washington, dep. neurological surgery, Seattle WA 98195, United States
M. A HOWARD - Univ. Washington, dep. neurological surgery, Seattle WA 98195, United States
J. A MOLLOY - Univ. Washington, dep. neurological surgery, Seattle WA 98195, United States
R. C RITTER - Univ. Washington, dep. neurological surgery, Seattle WA 98195, United States
E. G QUATE - Univ. Washington, dep. neurological surgery, Seattle WA 98195, United States
G. T GILLIES - Univ. Washington, dep. neurological surgery, Seattle WA 98195, United States
Resource Type: Journal article
Publication Details: Medical physics (Lancaster), Vol.17(3), pp.405-415
Publisher: American Association of Physicists in Medicine; Melville, NY
DOI: 10.1118/1.596520
PMID: 2200950
ISSN: 0094-2405
eISSN: 2473-4209
Language: English
Date published: 1990
Academic Unit: Neurology; Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
Record Identifier: 9984020796702771

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