Journal article
Nonuremic calciphylaxis associated with histologic changes of pseudoxanthoma elasticum
The American journal of dermatopathology, Vol.35(1), pp.106-108
02/2013
DOI: 10.1097/DAD.0b013e31826330db
PMID: 22892472
Abstract
Calciphylaxis is a rare condition characterized by medial calcification of small- and medium-sized vessels that subsequently leads to ischemic necrosis. Calciphylaxis most often occurs in patients with end-stage renal disease and secondary hyperparathyroidism. We present a unique case of calciphylaxis in which the patient did not have end-stage renal disease. Instead, primary hyperparathyroidism and/or alcoholic cirrhosis were the more likely causes of her calciphylaxis. In addition, our case demonstrated not only calciphylaxis but also fragmentation and calcification of elastic fibers within the dermis, changes that are most often seen in pseudoxanthoma elasticum. This is the first reported case of calciphylaxis, to our knowledge, with histopathologic changes of pseudoxanthoma elasticum in a patient who is nonuremic.
Details
- Title: Subtitle
- Nonuremic calciphylaxis associated with histologic changes of pseudoxanthoma elasticum
- Creators
- Kristen H Fernandez - Department of Dermatology, University of Missouri, Columbia, MO 65212, USA. kristen.1h.fernandez@gmail.comVincent LiuBrian L Swick
- Resource Type
- Journal article
- Publication Details
- The American journal of dermatopathology, Vol.35(1), pp.106-108
- Publisher
- United States
- DOI
- 10.1097/DAD.0b013e31826330db
- PMID
- 22892472
- ISSN
- 0193-1091
- eISSN
- 1533-0311
- Language
- English
- Date published
- 02/2013
- Academic Unit
- Dermatology; Pathology
- Record Identifier
- 9984025334702771
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