Normal coronary arteries in patients with systolic heart failure who have higher body mass index

Prasanna Venkatesh; Janos Molnar; Paari Swaminathan; Sandeep Khosla; Rohit Arora

doi:10.1016/j.hrtlng.2006.10.004

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Normal coronary arteries in patients with systolic heart failure who have higher body mass index

Journal article

Peer reviewed

Normal coronary arteries in patients with systolic heart failure who have higher body mass index

Prasanna Venkatesh, Janos Molnar, Paari Swaminathan, Sandeep Khosla and Rohit Arora

Heart & lung, Vol.36(2), pp.125-131

03/01/2007

DOI: 10.1016/j.hrtlng.2006.10.004

PMID: 17362793

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Abstract

Previous research has shown an association between higher body mass index (BMI) and lower mortality in patients with heart failure (HF). We compared the prevalence of angiographic coronary artery disease (CAD) and risk factors in obese versus non-obese patients with HF. Eighty-four consecutive patients with systolic HF who underwent coronary anqioqraphy in a sinqle institution were cateqorized by BMI into non-obese (BMI < 30, n = 42) and obese (BMI ≥ 30, n = 42) subjects. Chi-square analysis demonstrated a greater prevalence of normal coronary arteries and a lesser prevalence of CAD in the obese patients compared with the non-obese patients (64% [27/42] of obese patients vs 43% [1 8/42] non-obese patients had normal coronary arteries, P < .05). Among the obese patients, the subgroup with normal coronary arteries had a higher BMI (39 vs 32, P < .001) and was younger (51 vs 63 years, P < .005) compared with those with CAD. Although the prevalence of significant CAD (>50% diameter stenosis) was similar between obese and non-obese patients, the obese subgroup had a lower high-density lipoprotein (39 vs 49 mg/dL, P < .05). Angiographically normal coronary arteries were more prevalent in patients with systolic HF who have a higher BMI.

Correlation analysis

Health risk assessment

Heart failure

Obesity

Patients

Weight

Details

Title: Subtitle: Normal coronary arteries in patients with systolic heart failure who have higher body mass index
Creators: Prasanna Venkatesh - Rosalind Franklin University of Medicine and Science
Janos Molnar - Rosalind Franklin University of Medicine and Science
Paari Swaminathan - Rosalind Franklin University of Medicine and Science
Sandeep Khosla - Rosalind Franklin University of Medicine and Science
Rohit Arora - Rosalind Franklin University of Medicine and Science
Resource Type: Journal article
Publication Details: Heart & lung, Vol.36(2), pp.125-131
Publisher: Elsevier Science Ltd
DOI: 10.1016/j.hrtlng.2006.10.004
PMID: 17362793
ISSN: 0147-9563
eISSN: 1527-3288
Language: English
Date published: 03/01/2007
Academic Unit: Internal Medicine
Record Identifier: 9984366372402771

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