Norwood Procedure Performed on a Patient With Trisomy 13

Norihiko Oka; Takamichi Inoue; Miyuki Shibata; Takeshi Yoshii; Yuki Nakamura; Haruna Araki; Yoshikiyo Matsunaga; Tomoki Tamura; Keiichi Itatani; Tetsuya Horai; Tadashi Kitamura; Shinzo Torii; Kagami Miyaji

doi:10.1536/ihj.15-186

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Norwood Procedure Performed on a Patient With Trisomy 13

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Norwood Procedure Performed on a Patient With Trisomy 13

Norihiko Oka, Takamichi Inoue, Miyuki Shibata, Takeshi Yoshii, Yuki Nakamura, Haruna Araki, Yoshikiyo Matsunaga, Tomoki Tamura, Keiichi Itatani, Tetsuya Horai, …

International heart journal, Vol.57(1), pp.121-122

01/01/2016

DOI: 10.1536/ihj.15-186

PMID: 26673438

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Abstract

Trisomy 13 is associated with a variety of congenital anomalies, some of which are life-threatening and related to poor prognosis. Therefore, cardiac surgery is rarely offered to these patients, especially to those with complex cardiac anomalies. We report the case of a neonate weighing 2324 g who was born with severe congenital heart defects. Transthoracic echocardiography revealed the diagnoses of asplenia, single ventricle, aortic stenosis, coarctation of the aorta, hypoplastic aortic arch, and total anomalous pulmonary venous return. She was hemodynamically unstable. Palliative Norwood procedure with right ventricle pulmonary artery conduit (RV-PA conduit) was performed at the age of 1 day to save her life. On postoperative day 7, chromosome analysis revealed trisomy 13. Echocardiography revealed good heart function; stable hemodynamic status was achieved with minimal amounts of inotropic agents. However, she developed anuria, which did not improve despite situational possible interventions, including peritoneal dialysis and continuous hemodiafiltration. On postoperative day 37, she succumbed to sudden cardiorespiratory failure. Nevertheless, this case indicates that a neonate with trisomy 13 can have a better chance at survival with cardiac surgery such as the Norwood procedure with an RV PA conduit.

Cardiac & Cardiovascular Systems

Cardiovascular System & Cardiology

Life Sciences & Biomedicine

Science & Technology

Details

Title: Subtitle: Norwood Procedure Performed on a Patient With Trisomy 13
Creators: Norihiko Oka - Kitasato University
Takamichi Inoue - Kitasato University
Miyuki Shibata - Kitasato University
Takeshi Yoshii - Kitasato University
Yuki Nakamura - Kitasato University
Haruna Araki - Kitasato University
Yoshikiyo Matsunaga - Kitasato University
Tomoki Tamura - Kitasato University
Keiichi Itatani - Kitasato University
Tetsuya Horai - Kitasato University
Tadashi Kitamura - Kitasato University
Shinzo Torii - Kitasato University
Kagami Miyaji - Kitasato University
Resource Type: Journal article
Publication Details: International heart journal, Vol.57(1), pp.121-122
DOI: 10.1536/ihj.15-186
PMID: 26673438
ISSN: 1349-2365
eISSN: 1349-3299
Publisher: Int Heart Journal Assoc
Number of pages: 2
Grant note: 25861232 / Grants-in-Aid for Scientific Research; Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT); Japan Society for the Promotion of Science; Grants-in-Aid for Scientific Research (KAKENHI)
Language: English
Date published: 01/01/2016
Academic Unit: Cardiothoracic Surgery
Record Identifier: 9985164330502771

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