Journal article
Novel approaches to linkage mapping
Current Opinion in Genetics & Development, Vol.5(3), pp.335-341
1995
DOI: 10.1016/0959-437X(95)80048-4
PMID: 7549428
Abstract
The recent progress seen in the development of high-quality genetic markers and high-density human genetic maps is facilitating new strategies for mapping disease-causing and disease-susceptibility genes. These strategies, which include homozygosity mapping, DNA pooling, and the utilization of linkage disequilibrium, have been successfully applied to the mapping and fine mapping of several loci causing diseases segregating in genetically isolated populations.
Details
- Title: Subtitle
- Novel approaches to linkage mapping
- Creators
- Val C Sheffield - Department of Pediatrics Division of Medical Genetics, University of Iowa, Iowa City, Iowa 52242, USADarryl Y Nishimura - Department of Pediatrics Division of Medical Genetics, University of Iowa, Iowa City, Iowa 52242, USAEdwin M Stone - Department of Opthalmology, University of Iowa, Iowa City, Iowa 52242, USA
- Resource Type
- Journal article
- Publication Details
- Current Opinion in Genetics & Development, Vol.5(3), pp.335-341
- DOI
- 10.1016/0959-437X(95)80048-4
- PMID
- 7549428
- NLM abbreviation
- Curr Opin Genet Dev
- ISSN
- 0959-437X
- eISSN
- 1879-0380
- Publisher
- Elsevier Ltd
- Language
- English
- Date published
- 1995
- Academic Unit
- Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Medical Genetics and Genomics; Ophthalmology and Visual Sciences
- Record Identifier
- 9983980018702771
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